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Taking progestogens during high-risk pregnancy could reduce preterm birth


Taking progestogens during high-risk pregnancy could reduce preterm birth
Taking progestogens - steroid hormones - during pregnancy could reduce the risk of preterm birth in high-risk single baby pregnancies, research has shown.
Although these compounds have been in use for some time, results of individual clinical trials investigating their effectiveness in preventing preterm birth have been conflicting, and so further evaluation of the research evidence was needed.
University of York researchers led the Evaluating Progestogens for Prevention of Preterm Birth International Collaborative (EPPPIC) project, a systematic review which brought together and re-analysed datasets from 31 clinical trials of progestogens, including more than 11,000 women and 16,000 babies worldwide. ....

Lesley Stewart , Zarko Alfirevic , Emily Henderson , University Of York Centre For , University Of York , Outcomes Research Institute , Prevention Of Preterm Birth International Collaborative , Evaluating Progestogens , Preterm Birth International Collaborative , Project Principal Investigator , Coordinating Editor , Cochrane Pregnancy , Patient Centered Outcomes Research , லெஸ்லி ஸ்டீவர்ட் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் யார்க் மையம் க்கு , பல்கலைக்கழகம் ஆஃப் யார்க் , ஔட்கம்ஸ் ஆராய்ச்சி நிறுவனம் , ப்ராஜெக்ட் ப்ரிந்ஸிபல் புலனாய்வாளர் , ஒருங்கிணைத்தல் ஆசிரியர் , கோக்ரேன் ப்ரெக்நெந்ஸீ , நோயாளி மையமாக ஔட்கம்ஸ் ஆராய்ச்சி ,