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Lipid identified in human breast milk may play important role in early childhood weight


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IMAGE: Elvira Isganaitis, MD, is a staff physician at Joslin Diabetes Center and Assistant Professor of Pediatrics at Harvard Medical School
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Credit: Joslin Communications
BOSTON - (December 02, 2020) - A lipid metabolite called 12,13-diHOME is in human breast milk and appears to be associated with beneficial infant weight gain and body composition in the early postnatal period. Moreover, maternal fitness, specifically exercise, appears to boost levels of the metabolite in breast milk and so might benefit their offspring. This finding was published online by The
Journal of Clinical Endocrinology and Metabolism.
The authors of the study propose that 12,13-diHOME, as well as linked pathway metabolites from breast milk, have a protective effect against obesity development in offspring. They also suggest that a single bout of maternal exercise may boost levels of the metabolite in breast milk and that may translate into benefits fo ....

United States , Elvira Isganaitis , Michael Rudolph , Abena Darkwah , Yu Hua Tseng , Matthew Lynes , Valerie Bussberg , Niven Narain , Vladimir Tolstikov , Ellen Demerath , Michael Kiebish , University Of Oklahoma Health Sciences Center , Professor Of Pediatrics At Harvard Medical School , Harold Hamm International Prize , National Institutes Of Health , Diabetes Research Center , Harvard Medical School , Diabetes Research Centers , University Of Oklahoma , Joslin Diabetes Center , University Of Minnesota , Harold Hamm Diabetes Center , United States Army Medical Research , Clinical Endocrinology , Assistant Professor , David Fields Phd ,