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New HIV reporter model: Visualizing HIV viral dynamics in cells with dual fluorescence

Kumamoto University researchers have developed a novel viral reporter system named HIV-Tocky (Timer of Cell Kinetics and Activity). This innovative system allows for real-time visualization of HIV dynamics post-viral infection. ....

Omnia Reda , Yorifumi Satou , Communications Biology , Kumamoto University , Research Center , Cell Kinetics , Joint Research Center , Human Retrovirus Infection ,

CMV and herpes are latent viruses that could help create new vaccines

Latent viruses like CMV enter our bodies while we re young; after that, they establish a lifelong infection that researchers are only just beginning to understand. ....

United States , University Of Arizona , City Of , United Kingdom , Felicia Goodrum , Mark Henle , Gideon Dobson , Kathleen Muldoon , Yorifumi Satou , Greg Smith , Foundation For Blind Children , Geisel School Of Medicine At Dartmouth , Imperial College London , Midwestern University , Geisel School , Blind Children , Herpes Simplex Virus Type , South America , T Cell Lymphotropic Virus , Infectedt Cells , Understandingt Cells ,

Scientists Map Link Between Virus and Rare Type of Leukaemia

Study casts new light on the mechanism for how HTLV-1 can evade the immune system to cause adult T cell leukaemia/lymphoma. ....

United States , United Kingdom , City Of , Yorifumi Satou , Kumamoto University , Imperial College London , Humant Lymphotropic , Clinical Investigation , Can Lead , South America , Hematology Haematology , Leukemia Leukaemia , Uk Site Content United Kingdom , United Kingdom , Humant Cell Lymphotrophic Virus , Tlv Humant Cell Lymphotrophic Virus , Alignant Neoplasia , Alignant Neoplasm , Viral Infection , Viral Illness , T Cell , Medical Literature , Social Issues ,

Researchers map how the HTLV-1 virus causes a rare leukemia in some people

An international team have mapped how the HTLV-1 virus causes a rare leukemia in some people, providing clues on how to stop it happening. ....

City Of , United Kingdom , Yorifumi Satou , Emily Henderson , Kumamoto University , Imperial College London , Study Co , Department Of Life Sciences At Imperial , Clinical Investigation , Study Co Lead Researcher , Life Sciences , T Cell ,

How a Virus Induces a Rare Leukemia Offers New Therapeutic Clues

Scientists have uncovered how the HTLV-1 virus provokes a rare form of leukemia called adult T-cell leukemia/lymphoma by transforming the host’s normal T lymphocytes into a malignant state. Comparing gene expression in T cells from virus-free donors, healthy carriers of the virus, and patients with ATL, the authors show the virus increases the expression of genes involved in cell proliferation, providing new therapeutic targets that can be drugged to halt the chronic activation of T cells. ....

City Of , United Kingdom , Yorifumi Satou , Kumamoto University , Imperial College London , Clinical Investigation , Masahiro Ono ,