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Guangzhou, April 8, 2021: New journal BIO Integration (BIOI) publishes its fifth issue, volume 2, issue 1. BIOI is a peer-reviewed, open access, international journal, which is dedicated to spreading multidisciplinary views driving the advancement of modern medicine. Aimed at bridging the gap between the laboratory, clinic, and biotechnology industries, it will offer a cross-disciplinary platform devoted to communicating advances in the biomedical research field and offering insights into different areas of life science, to encourage cooperation and exchange among scientists, clinical researchers, and health care providers. The issue contains an editorial, two mini review articles, two opinion articles and an interview offering insights into different areas of life science in both China and internationally: ....
Announcing a new publication for BIO Integration journal. In this opinion article the authors Daiyun Xu, Yonghui Lü, Yongxiao Li, Shengbin Li, Zhe Wang and Junqing Wang from Sun Yat-Sen University, Guangzhou, China discuss ferroptosis resistance in cancer. Ferroptosis is a lethal consequence of accumulated lipid peroxidation catalyzed by ferrous iron and oxygen. This unique cell death process appears to involve many diseases, such as neurodegeneration, ischemia/ reperfusion injury, kidney disease, and a druggable target in therapy-resistant cancers. Ferroptosis may provide hope for the treatment of as yet incurable diseases. However, ferroptosis susceptibility is linked to various regulation pathways. In this article the authors integrate the current understanding of signaling mechanisms for ferroptotic defences with a view to development of novel cancer therapeutic strategies. ....