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by Mark Derewicz February 2, 2021 . CHAPEL HILL – Many molecules in our bodies help our immune system keep us healthy without overreacting so much that our immune cells cause problems, such as autoimmune diseases. One molecule, called AIM2, is part of our innate immunity – a defense system established since birth – to fight pathogens and keep us healthy. But little was known about AIM2’s contribution to T cell adaptive immunity – defenses developed in response to particular pathogens and health problems we develop over the course of our lives. Now, UNC School of Medicine scientists co-led by Jenny Ting, PhD, the William Kenan Distinguished Professor of Genetics, and Yisong Wan, PhD, professor of microbiology and immunology, discovered that AIM2 is important for the proper function of regulatory T cells, or Treg cells, and plays a key role in mitigating autoimmune disease. Treg cells are a seminal population of adaptive immune cells that prevents an overzealou ....
Study: For regulating immunity, functioning of molecule in cells is crucial ANI | Updated: Jan 29, 2021 23:15 IST Washington [US], January 29 (ANI): Researchers of the University of North Carolina Health Care have discovered that AIM2 is significant for the legitimate capacity of regulatory T cells, or Treg cells, and assumes a critical part in moderating immune system sickness. Treg cells are an original populace of versatile insusceptible cells that forestalls an enthusiastic immune response, such as those that occur in autoimmune diseases. Many molecules in our bodies help our immune system keep us healthy without overreacting so much that our immune cells cause problems, such as autoimmune diseases. One molecule, called AIM2, is part of our innate immunity, a defense system established since birth to fight pathogens and keep us healthy. But little was known about AIM2 s contribution to T cell adaptive immunity defenses deve ....
E-Mail CHAPEL HILL, NC - Many molecules in our bodies help our immune system keep us healthy without overreacting so much that our immune cells cause problems, such as autoimmune diseases. One molecule, called AIM2, is part of our innate immunity - a defense system established since birth - to fight pathogens and keep us healthy. But little was known about AIM2 s contribution to T cell adaptive immunity - defenses developed in response to particular pathogens and health problems we develop over the course of our lives. Now, UNC School of Medicine scientists led by Jenny Ting, PhD, the William Kenan Distinguished Professor of Genetics, and Yisong Wan, PhD, professor of microbiology and immunology, discovered that AIM2 is important for the proper function of regulatory T cells, or Treg cells, and plays a key role in mitigating autoimmune disease. Treg cells are a seminal population of adaptive immune cells that prevents an overzealous immune response, such as those that o ....