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High-Sensitivity Troponin Assays May Stratify Risk in Chronic CAD

An exploratory analysis suggests an elevated troponin level may identify patients who would benefit from revascularization.

United kingdomCity ofYader sandovalAllan jaffeRyan wereskiJournal of the american college cardiologyMd minneapolis heart instituteUniversity of edinburghAmerican collegeBritish heart foundation centreCardiovascular scienceRoyal infirmaryRobust barometerMinneapolis heart instituteAbbott northwestern hospitalMayo clinic

Troponin Could Play Larger Role Predicting Risk in Stable CAD

Risk stratification with or without obstructive coronary disease

United kingdomUnited statesMayo clinic in rochesterCity ofAbbott northwestern hospitalYader sandovalColl cardiolNicholas millsAllan jaffeNicole louJournal of the american college cardiologyUniversity of edinburghMinneapolis heart instituteRoyal infirmaryAmerican collegeMayo clinic

hs-Troponins and the Chest Pain Guidelines: Experts Call for Clarification

The 2021 guidelines carved out a role for hs-cTn, but a group of concerned physicians says they need more detailed advice.

United statesYader sandovalLos angelesAllans jaffeMartha gulatiAmerican heart associationSinai medical centerAmerican college of cardiologyDrug administrationInternational federation of clinical chemistryEuropean society of cardiologyLaboratory medicine committeeAmerican collegeMayo clinicCedars sinai medical centerEuropean society

Higher Single-Sample hs-cTnT Threshold Can Safely Exclude MI

FDA rules require testing a hs-cTnT cutoff of 6 ng/L, not the 5 ng/L used in European studies. The good news is it still works.

Yader sandovalAllan jaffeEuropean society of cardiologyDrug administrationProblems causedEuropean societyAmerican collegeAmerican heart associationMayo clinicCardiovascular data mart biomarker cohortElecsys troponint genRoche diagnosticsTnt adjudication cohort

US Chest Pain Guidelines Will Change Practice, Though Gaps Remain

The great strengths of the document its breadth and inclusiveness are also chief causes for complaint.

New yorkUnited statesAndrew choiRohit moudgilYader sandovalDavidl brownRenee bullock palmerDeborah diercksKrishna patelMartha gulatiMd ut southwestern medical centerMd washington university school of medicineAmerican college of chest physiciansGeorge washington universityIcahn school of medicine at mount sinaiSociety for cardiovascular magnetic resonance

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