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Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. ....

United States , Nikhita Mudium , Nicolej Corbin Stein , Acta Neuropathologica , Jeffreyh Kordower , Jhodim Webster , Fredricp Manfredsson , Asta Zane , Rajesh Gupta , Gabriellem Childers , Acta Neuropathologica Communications , Department Of Neurology , Barrow Neurological Institute , Arizona State University , National Institutes Of Health , University Of Alabama At Birmingham , Ashley Harms , Associate Professor , Ya Ting Yang , Experimental Therapeutics , National Institutes , Interferon Gamma , Ouse Model , Multiple System Atrophy , Immune System , Natural Killer Cells ,