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Leveraging phosphorothioate backbone modification to optimize aptamer-drug conjugates for therapeutic agent delivery

Leveraging phosphorothioate backbone modification to optimize aptamer-drug conjugates for therapeutic agent delivery
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Xue Qiang Wang , Qiuxia Yang , Science China , National Science , Hangzhou Institute Of Medicine , Geometric Mean Fluorescence Intensity , Science China Press , Weihong Tan , Changzhou Institute , National Science Review ,

Phosphorothioate backbone modification enhances aptamer-drug conjugate for pancreatic cancer therapy

Pancreatic cancer is a complex and deadly solid tumor that poses significant challenges for both diagnosis and treatment. ....

Xue Qiang Wang , Megan Craig , Hangzhou Institute Of Medicine , Weihong Tan , Changzhou Institute ,