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Merck: Xevinapant Five-Year Data Show Survival Rate Nearly Doubled in Patients with Unresected LA SCCHN, When Added to Standard of Care

Not intended for US-, Canada- and UK-based media First randomized trial in decades to show significant improvement in overall survival in patients with LA SCCHN, reinforcing the transformative ....

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EMD Serono: Xevinapant Five-Year Data Show Survival Rate Nearly Doubled in Patients with Unresected LA SCCHN, When Added to Standard of Care

Not intended for UK-based media First randomized trial in decades to show significant improvement in overall survival in patients with LA SCCHN, reinforcing the transformative potential of xevinapant ....

United States , Kostenloser Wertpapierhandel , Le Tourneau , Amanda Hollinger , Sun Xs Tao , Jean Bourhis , Head Of Development Unit Oncology , Drug Administration , Department Head Of Radio , European Society Of Medical Oncology Congress , Merck Kga , Serono Inc , Neck Cancer Alliance , Merck Kgaa , University Hospital Of Lausanne , United Kingdom Based , European Society , Medical Oncology Congress , Department Head , University Hospital , Executive Director , Neck Cancer , Victoria Zazulina , Development Unit Oncology , Breakthrough Therapy Designation , Sunx S ,

Debiopharm Grants a Worldwide Exclusive License to Merck for the Development and Commercialization of Xevinapant

Debiopharm Grants a Worldwide Exclusive License to Merck for the Development and Commercialization of Xevinapant
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Xevinapant is the first Inhibitor of Apoptosis Proteins antagonist with FDA Breakthrough Therapy Designation for previously untreated locally advanced squamous cell carcinoma of the head and neck, in combination with current standard of care
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A Phase II trial reported that xevinapant plus chemoradiotherapy reduced risk of death by 51% vs standard of care in this patient population; Phase III TrilynX study initiated in September 2020
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Merck gains exclusive global development and commercialization rights; Debiopharm to receive €188 million upfront and up to €710 million in milestone, as well as royalty payments ....

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