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Successful elimination of falciparum malaria following the introduction of community-based health workers in Eastern Myanmar: A retrospective analysis

In this retrospective analysis, Aye Sandar Zaw and colleagues report the successful elimination of falciparum malaria following the introduction of community-based health workers in Eastern Myanmar ....

South Korea , United States , Jamesg Beeson , Rdts Alere , Oxford Tropical Research Ethics Committee Ox , Wellcome Trust Grant , World Health Organization , Burnet Institute , Department Of Health , Mahidol Oxford Tropical Medicine Research Programme , Department Of Health Do , Global Fund , Mekong Malaria Elimination Programme , National Malaria Control Programme , Greater Mekong , East Myanmar , Medical Action Myanmar , Eastern Myanmar , Creative Commons Attribution License , Medical Action , Wellcome Trust , Author Accepted Manuscript , Greater Mekong Subregion , World Health , Malaria Elimination Programme , Action Myanmar ,

Evaluation of portable devices for medicine quality screening: Lessons learnt, recommendations for implementation, and future priorities

Céline Caillet and co-authors discuss a Collection on use of portable devices for the evaluation of medicine quality and legitimacy. ....

United Kingdom , Rattanaphone Phetsouvanh , Sonalini Khetrapal , Mayfong Mayxay , Susann Roth , Government Of Australia Department Foreign Affairs , Wellcome Trust Grant , Communicable Disease Threats Trust Fund , Bureau Of Food , Asian Development Bank , World Health Organisation , Us Pharmacopeial Convention , Drug Department , University Of Health Sciences , Drug Quality Control Centre , Government Of Canada Department Foreign Affairs , Creative Commons Attribution License , Regional Malaria , Foreign Affairs , International Development , Open Access , Author Accepted Manuscript , Coronavirus Disease , World Health , Medicines Regulatory Authorities , Drug Inspection ,

Parasites may accumulate in spleens of asymptomatic individuals infected with malaria

Malaria, a disease caused mainly by the parasites Plasmodium falciparum and Plasmodium vivax, is associated with over 400,000 deaths each year. Previously, the spleen was assumed to mostly play a role in parasite destruction, as it eliminates malaria parasites after antimalarial treatment. A study published by Steven Kho and Nicholas Anstey at Menzies School of Health Research, Australia, and international colleagues, suggests that in chronic P. vivax infections, malaria parasites survive and replicate via a previously undetected lifecycle within the spleen. ....

France General , Steven Kho , Royal Society Wolfson Research , Wellcome Trust Grant , Research Article , Melinda Gates Foundation , French Institut National De La Sant , Australian National Health , Research Council Program Grant , Australian Department Of Foreign Affairs , Health Outcomes , Sauver La Vie Foundation , University Of Paris , Singapore National Medical Research Council , Nicholas Anstey , Menzies School , Health Research , Medical Research Council , Program Grant , Improving Health Outcomes , Tropical North , Australian Centre , Research Excellence , Malaria Elimination , Paris Ile De France Region , Evie Foundation ,

Higher rates of chronic pain in women linked to genetics

Credit: Esther Max, Flickr. Rotated from original.
Women may be at greater risk of experiencing chronic pain because the condition has a different genetic basis in men and women. Keira Johnston of the University of Glasgow and colleagues report these findings in a new study published April 8th in
PLOS Genetics.
Chronic pain is a common and potentially debilitating condition that tends to affect more women than men. To explore this disparity, researchers undertook the largest ever genetic study of chronic pain that analyzed women and men separately. They looked for genetic variants associated with chronic pain in 209,093 women and 178,556 men, and compared the results. In women, 31 genes were associated with chronic pain, while 37 genes were linked in men. A single gene was associated with chronic pain in both sexes. The researchers also investigated whether the activity of these genes was turned up or down in tissues known to be related to chronic pain. They found th ....

Keira Johnston , Royal College Of Physicians Edinburgh , Mental Health Data Pathfinder Award , Wellcome Trust Grant , Doctoral Training Programme Studentship , University Of Glasgow , National Institute Of Neurological Disorders , United Kingdom , United Kingdom Fellowship , Royal College , Training Programme Studentship , Lister Prize Fellowship , Health Data Pathfinder Award , Pathfinder Award , National Institute , Neurological Disorders , அரச கல்லூரி ஆஃப் மருத்துவர்கள் எடின்பர்க் , மன ஆரோக்கியம் தகவல்கள் பாத்ஃபைண்டர் விருது , வெல்கம் நம்பிக்கை மானியம் , பல்கலைக்கழகம் ஆஃப் கிளாஸ்கோ , தேசிய நிறுவனம் ஆஃப் நரம்பியல் கோளாறுகள் , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது கிஂக்டம் கூட்டுறவு , அரச கல்லூரி , பாத்ஃபைண்டர் விருது , தேசிய நிறுவனம் ,