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Words. life couldn t be simpler. reporter: some call her one of the finest mezzo-sopranos in the world. 23 years ago she left her native shanghai and came to the united states to pursue her dream to perform music. she didn t have much to call her own. $45, and two big suitcases. reporter: chou won a scholarship and fell in love with the opera. she s performed in operas all over the world. her performance as ruth in the bone setter s daughter changed her life. in the open i fell off the stage, and this pain above my back, and just fingers for long time. then the next day the doctor called, my doctor called me, he said, we had shadow on your lung. and i said oh, that s ridiculous. i ve been singing. i said, no problem. reporter: cao was diagnosed with stage iv lung cancer, even ....
Though she s never smoked. realistically, how long do i have? and she said, well, look at it six months. reporter: the cancer had spread all over her body, the largest tumor was located behind her vocal chords. they also found 24 separate brain tumors. even when i find out about 24 tumors, still i think i had this like blind faith. reporter: cao decided to fight. during her treatment, cao fell in love, again. this time, though, with the doctor who saved her life. well, the person who actually went through the trouble to save my voice is now, that person is my husband. reporter: she never gave up hope. or her desire to sing. it s been incredible, unbelievable journey. reporter: dr. sanjay gupta, cnn. love in the most unlikely places. well cao tells cnn she s just had another setback unfortunately but she s determined to continue to fight ....