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First steps toward a whole-body map of molecular responses to exercise

First steps toward a whole-body map of molecular responses to exercise
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Paul Piehowski , Steven Carr , Tyler Sagendorf , James Sanford , Josh Adkins , Wei Jun Qian , Pacific Northwest National Laboratory , Broad Institute , Harvard University , Environmental Molecular Sciences Laboratory , Nathan Johnsoni Pacific Northwest National Laboratory , National Institutes Of Health Common Fund , Molecular Transducers Of Physical Activity Consortium Motr , Massachusetts Institute Of Technology , Department Of Energy Office Science , Nathan Johnsoni Pacific Northwest National , National Institutes , Health Common Fund , Molecular Transducers , Physical Activity Consortium , Massachusetts Institute , Energy Office , Gina Many ,

First Steps Toward a Whole-Body Map of Molecular Responses to Exercise

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training. ....

Wei Jun Qian , Paul Piehowski , Steven Carr , Josh Adkins , James Sanford , Tyler Sagendorf , Pacific Northwest National Laboratory , Environmental Molecular Sciences Laboratory , Molecular Transducers Of Physical Activity Consortium Motr , National Institutes Of Health Common Fund , Broad Institute , Harvard University , Department Of Energy Office Science , Massachusetts Institute Of Technology , National Institutes , Health Common Fund , Molecular Transducers , Physical Activity Consortium , Massachusetts Institute , Energy Office , Gina Many ,

Google Your Brain

The Allen Brain Atlas, a genome-wide map of the mouse brain on the Internet, has been hailed as “Google of the brain.” The atlas now has a companion or the brain’s working molecules, a sort of pop-up book of the proteins, or proteome map, that those genes express. ....

Mark Chin , Richardd Smith , Wei Jun Qian , Desmond Smith , Vladislava Petyuk , Environmental Molecular Sciences Laboratory , Department Of Energy Pacific Northwest National Laboratory , Genome Research , Pacific Northwest National Laboratory , David Geffen School Of Medicine , Allen Brain Atlas , Battelle Fellow , Geffen School , Pacific Northwest National , National Institutes , Molecular Sciences Laboratory , Neuroscience Gateway , Genetics Amp Molecular Biology ,

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

In 2012, University of Alabama at Birmingham researcher Anath Shalev, M.D., reported that a decades-old blood pressure medication called verapamil completely reversed diabetes in animal models. ....

Cornell University , New York , United States , Praveen Sethupathy , Wei Jun Qian , Junqin Chen , Eugenec Gwaltney , Lily Ramsey , Guanlan Xu , Brian Lu , Diabetes Research , National Institutes Of Health , Department Of Medicine , Marnixe Heersink School Of Medicine , University Of Alabama At Birmingham , National Institute Of Diabetes , Division Of Endocrinology , Diabetes Research Center Pilot , Diabetes Center , Department Of Medicine Division Endocrinology , Pacific Northwest National Laboratory , Anath Shalev , Medicine Division , National Institutes , Research Center Pilot , National Institute ,

In Type 1 diabetes, verapamil prevents decline of IGF-1 and promotes beta-cell IGF-1 signaling

These results add an additional, mechanistic aspect to further explain how the decades-old blood pressure medication verapamil can preserve beta cell function in Type 1 diabetes patients by affecting the hormone insulin-. ....

Cornell University , New York , United States , Brian Lu , Junqin Chen , Praveen Sethupathy , Guanlan Xu , Eugenec Gwaltney , Wei Jun Qian , National Institutes Of Health , Division Of Endocrinology , Department Of Medicinedivision Endocrinology , Diabetes Center , Department Of Medicine , Pacific Northwest National Laboratory , Marnixe Heersink School Of Medicine , National Institute Of Diabetes , Department Of Medicine Division Endocrinology , Diabetes Research , Diabetes Research Center Pilot , University Of Alabama At Birmingham , Stream Diabetes , Anath Shalev , Medicine Division , National Institutes , Research Center Pilot ,