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Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans. ....

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Common diabetes drug shows promise as treatment for COVID-19 lung inflammation

Researchers identify molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19. ....

San Diego , United States , University Of California San Diego , Moshe Arditi , Pejman Soroosh , Los Angeles , Weixuan Chen , Sarah Kang , Raphaella Gatchalian , Warreng Tourtellote , Elsa Sanchez Lopez , Dorit Trudler , John Teijaro , Wanda Hildyard , Melissa Luevanos , Yi Zhang , Alexandra Rundberg Nilsson , Michael Karin , Timothyr Crother , Stuarta Lipton , Sanchez Lopez , Gavin Lewis , Scripps Research Institute , Sinai Medical Center , Department Of Orthopedic Surgery , Janssen Research Development ,