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Researchers Return to Alzheimer's Vaccines

Breakthrough Alzheimer’s treatments that remove toxic proteins from the brain have revived interest in vaccines to treat the memory-robbing disease, potentially offering a cheaper, easy-to-administer option for millions of people, according to interviews with 10 scientists and company executives. ....

United States , Julie Steenhuysen , Reisa Sperling , Eli Lilly , Michael Rafii , Andrea Pfiefer , Walter Koroshetz , Caroline Humer , University Of Southern California , Bristol Myers Squibb , Drug Administration , Us National Institutes Of Health , Mass General Brigham , Bristol Myers , Bill Berkrot , Alzheimers Disease , Lzheimer Disease , Biologic Therapy , Patient Safety , Antidementia Agents , Tau Proteins , Amyloid Beta , Monoclonal Antibody ,

FOCUS-Researchers return to Alzheimer's vaccines, buoyed by recent drug success

FOCUS-Researchers return to Alzheimer's vaccines, buoyed by recent drug success
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United States , Eli Lilly , Walter Koroshetz , Andrea Pfiefer , Michael Rafii , Reisa Sperling , Us National Institutes Of Health , Bristol Myers Squibb , University Of Southern California , Drug Administration , Breakthrough Alzheimer , Mass General Brigham ,

Researchers return to Alzheimer's vaccines, buoyed by recent drug success

Breakthrough Alzheimer’s treatments that remove toxic proteins from the brain have revived interest in vaccines to treat the memory-robbing disease, potentially offering a cheaper, easy-to-administer option for millions of people, according to interviews with 10 scientists and company executives. Clinical trials are underway or completed for at least seven Alzheimer’s vaccines designed to harness the immune system to rid the brain of the disease-related proteins beta amyloid or tau, a review of the U.S. government’s ClinicalTrials.gov database found. The renewed interest in Alzheimer's vaccines follows a promising first attempt more than 20 years ago that was abandoned after 6% of study volunteers developed life-threatening brain inflammation known as meningoencephalitis. ....

United States , Michael Rafii , Andrea Pfiefer , Julie Steenhuysen , Caroline Humer , Reisa Sperling , Eli Lilly , Walter Koroshetz , Bristol Myers Squibb , Drug Administration , University Of Southern California , Us National Institutes Of Health , Mass General Brigham , Bristol Myers , Bill Berkrot , Immune Response ,