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Italian organic food for Hanoi consumers – Talk Vietnam

Italian organic food for Hanoi consumers – Talk Vietnam
talkvietnam.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from talkvietnam.com Daily Mail and Mail on Sunday newspapers.

Han I , Republic Of , Phan Thuy Linh , Ricardo Cozzo , Thien Trang , Hai Ba Trung , Nam Tu Liem , Co Ltd , Organic Week , Italian Bioagricoop , Vinhomes Times City , Vietnamese Government , Phan Nguyen Trading Investment , Hanoi Times , Thi Thien Trang , Nam Tu Liem District ,

VinFast: behind Vietnam's rapid-fire automotive dream

VinFast: behind Vietnam's rapid-fire automotive dream
paultan.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from paultan.org Daily Mail and Mail on Sunday newspapers.

United States , France General , Republic Of , Han I , Le Thuy , Qu Ng Bì , Hai Phong , Hi Phòvm , South Korea , Shawn Calvert , Vinfast Jim Deluca , Thierry Chesnot Getty , Pham Nhat Vuong , Roy Flecknell , Jim Deluca , Vinfast Dave Lyon , David Lyons , Kevin Fisher , Thuy Le , Dave Lyon , David Beckham , Vincom Centre , Times City , Vincom Mega Mall , Mid Valley Megamall , Vinhomes Times City ,

Distant residues modulate conformational opening in SARS-CoV-2 spike protein

The novel coronavirus (SARS-CoV-2) pandemic resulted in the largest public health crisis in recent times. Significant drug design effort against SARS-CoV-2 is focused on the receptor-binding domain (RBD) of the spike protein, although this region is highly prone to mutations causing therapeutic resistance. We applied deep data analysis methods on all-atom molecular dynamics simulations to identify key non-RBD residues that play a crucial role in spike−receptor binding and infection. Because the non-RBD residues are typically conserved across multiple coronaviruses, they can be targeted by broad-spectrum antibodies and drugs to treat infections from new strains that might appear during future epidemics.

The MD trajectories are available from Zenodo at [doi.org/10.528c1/zenodo.5052691][1]. The codes and the residue correlation data used in this study are available from GitHub at <https://github.com/dhimanray/COVID-19-correlation-work>. All further details about the methods ....

Han I , Republic Of , South Africa , United States , United Kingdom , Trevor Gokey , Minh Khai , University Of California , Molecular Science Software Institute , World Health Organization , Vingroup Big Data Institute , World Health , Middle East , Molecular Mechanics , Graphical User Interface , Multiple Alignment , Fast Fourier Transform , Aligned Structural Homologs , Irvine High Performance Computing , Biomedical Informatics , Vinhomes Times City , Creative Commons Attribution License ,