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Patient collaboration in COVID-19 research: translating ideas to reality

Involving patients in all stages of health data research is a noble aim; however,
there are not too many examples of it being successfully put into practice particularly
not in real-time pandemic surveillance. In November, 2020, the Early Pandemic Evaluation
and Enhanced Surveillance of COVID-19 (EAVE II) team created a unique collaboration,
inviting a Public Advisory Group (PAG) of 15 patient and public contributors to work
alongside university and Public Health Scotland staff to provide vital perspectives
of the public on all areas of their COVID-19 research. ....

United Kingdom , City Of , David Weatherill , Sandra Jayacodi , Aziz Sheikh , Lana Woolford , Lynn Laidlaw , International Severe Acute Respiratory Infection Consortium , University Of Edinburgh , Imperial Biomedical Research Centre Public Advisory Panel , Long Covid Scotland Action Group , Public User Group , Paul Bradbury Caia Image Science Photo Library , Professor Of Primary Care Research , Research Collaboration Collaborative Leadership , United Kingdom National Health Service , Usher Institute , University Of Glasgow , Elsevier Ltd , Asthma United Kingdom Centre For Applied Research , Royal College Of Anaesthetists , Public Health Scotland , Public Advisory Group , Royal College Of Surgeons , Early Pandemic Evaluation , Enhanced Surveillance ,

Lecanemab for Alzheimer's disease: tempering hype and hope

The Alzheimer s disease community has become accustomed to false hope, disappointment,
and controversy. With an estimated 55 million people worldwide affected by dementia,
the need for an effective treatment is undeniable. But efforts to develop a drug that
can modify the course of Alzheimer s disease, by using antibodies to clear amyloid-beta
(Aβ) from the brain, have endured numerous setbacks over the past 20 years. Almost
a decade ago, the first anti-Aβ antibodies tested in phase 3 trials, bapineuzumab
and solanezumab, did not improve clinical outcomes in mild to moderate Alzheimer s
disease. ....

San Francisco , United States , Alzheimers Dement , Centre Jean Perrin , Drug Administration , Lancet Commission , Science Photo Library , Elsevier Ltd , Clinical Trials , Clinical Dementia Rating Sum , View Large , Jean Perrin , Science Photo ,

Opioid use and sleep apnoea

Opioid prescriptions in the USA have fallen over the past decade or so. But the numbers
are still enormous. In 2020, US pharmacies filled more than 140 million prescriptions
for opioids, enough to medicate 43% of the population. Some 10 million Americans are
thought to misuse opioids, a category of drug that includes heroin, methadone, and
morphine. ....

United States , Nordrhein Westfalen , Lynn Webster , Douglas Sacha , Elsevier Ltd , State Opioid Response , Senior Fellow , View Large , Chief Physician , Medical Director , Sleep Medicine , Respiratory Care , Hospital Bethanien , Lancet Respiratory ,

Silent Pandemic

It takes less than a quarter of an hour for Silent Pandemic to give up on the pharmaceutical
industry. First we hear from Ella Balasa, a 29-year-old American who is finding it
increasingly difficult to overcome the bacterial infections related to her cystic
fibrosis. She faces the frightening prospect that what is now difficult will soon
become impossible. We then cross the Atlantic for an interview with Sally Davies,
UK Special Envoy on Antimicrobial Resistance, who notes that there is a lag of at
least 10 years between the identification of an actionable target and the entry into
the market of a drug aimed at the target. ....

United States , United Kingdom , Muhammad Zaman , Sally Davies , Michael Wech , Ella Balasa , Isaac Stoner , Christine Najjuka , Harvard University Cambridge , Makerere University Kampala , Dennis Kunkel Microscopy Science Photo Library , International Health At Boston University , Duke Center , Elsevier Ltd , Silent Pandemic , United Kingdom Special Envoy , Antimicrobial Resistance , Octagon Therapeutics , Harvard University , Antimicrobial Stewardship , Infection Prevention , Saharan Africa , Makerere University , Ramanan Laxminarayan , Advisory Council , Combating Antimicrobial Resistance ,

Dilip Mahalanabis

Paediatrician who pioneered the use of oral rehydration therapy. Born on Nov 12, 1934
in what is now Kishoreganj, Bangladesh, he died on Oct 16, 2022 in Kolkata, India,
aged 87 years. ....

United States , United Kingdom , Harvard University , West Bengal , International Center , City Of , Dilip Mahalanabis , David Nalin , Tahmeed Ahmed , Shanta Dutta , Johns Hopkins University , Society For Applied , School Of Medicine , University Of Calcutta , Prince Mahidol Award In Public Health , Public Health , Research Investigator , Clinical Sciences Division , Diarrhoeal Disease Control Programme , Pollin Prize For Pediatric Research , Department Of Global Health , Senior Lecturer In Global Health , Elsevier Ltd , Kothari Centre Of Gastroenterology , School Of Hygiene , International Centre For Diarrhoeal Disease Research ,