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Risk Factors Could Inform BTK Inhibitor and Venetoclax Sequencing in CLL/SLL

Changchun Deng, MD, PhD, discusses factors to consider when sequencing covalent BTK inhibitors and venetoclax in patients with CLL/SLL. ....

United States , Oncology Program At Case Comprehensive Cancer Center , University Hospitals Seidman Cancer Center , Changchun Deng , Immune Oncology Program , Case Comprehensive Cancer Center , Covalent Btk Inhibitors , Chronic Lymphocytic Leukemia Cll , Small Lymphocytic Lymphoma ,

Targeted Therapies for CLL Can Lead to Improved Patient Outcomes

There was a marked increase in the prevalence of targeted therapy among patients with chronic lymphocytic leukemia (CLL), which corresponded to positive overall survival rates observed in the study. ....

United Kingdom , United States , Image Credit , North America , British Columbia , Trageted Therapy ,

SLS009 Plus Venetoclax/Azacitidine Produces Responses in R/R AML, Including ASXL1+ Disease

SLS009 plus venetoclax and azacitidine elicited responses in patients with relapsed/refractory AML, particularly in those harboring ASXL1 mutations. ....

Angelos Stergiou , Life Sciences Group , Sciences Group , Hematologic Oncology , Acute Myeloid Leukemia ,

Venetoclax Monotherapy Leads to Durable Responses in Relapsed, Refractory CLL

The data showed notable responses, even among patients living with chronic lymphocytic leukemia (CLL) who had previous exposure to B-cell receptor–associated kinase inhibitors, the authors said.
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Venetoclax Venclexta , Pharmacyclics Johnson , Abbvie Genentech , Image Credit , Brci Pretreated , Bcri Naïve , Venetoclax Monotherapy ,

Primary Analysis of the SYMPATICO trial in Mantle Cell Lymphoma

Focusing on mantle cell lymphoma, Lori A. Leslie, MD, reviews the primary analysis of the SYMPATICO trial investigating ibrutinib-venetoclax combination therapy. ....

Lori Leslie , Jamesk Mccloskey , Gloria Leslie , Hackensack University Medical Center , John Theurer Cancer Center , Research Programs , Peer Exchange , Hackensack University Medical , Associate Professor , Indolent Lymphoma , While Bruton , Mash 2023 , Sympatico Study , Sympatico Trial , Mantle Cell Lymphoma , Btk Inhibitors , Combination Therapy ,