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'Common' medication nonadherence in CV trials impacts outcomes, regardless of intervention

Two analyses of large randomized controlled trials suggest that participants not taking medications as prescribed may influence treatment effects and impact study findings, researchers reported.In analyses assessing medication nonadherence for the ISCHEMIA and MASTER DAPT trials, researchers found that the detrimental effect of nonadherence — worse health status — was consistent among ....

Coll Cardiol , Danielj Lauer , Johna Spertus , Usman Baber , University Of Missouri , Kansas City School Of Medicine , University Of Oklahoma Health Sciences Center , Vascular Disease Research , Oklahoma Health Sciences Center , Endowed Chair , Missouri Kansas City School , Morisky Green Levine Medication Adherence Scale , Seattle Angina ,