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In a large population-based observational study, Nathalie Conrad and colleagues1 showed the association between 19 autoimmune diseases and 12 cardiovascular diseases (CVDs) with data from about 22 000 000 people in the UK. However, we are concerned about the possibly confusing message caused by treating several CVDs as a composite outcome in this study. ....
Coronaviruses are a strand of viral illnesses that produce respiratory disease. The strand behind COVID-19, which produced a pandemic drawing international attention, differs from the other coronavirus strands. COVID-19 produces acute and severe respiratory syndromes. 1 There has been a strong link to patients developing myocarditis following COVD-19 diagnosis. The coronavirus SARS-CoV-2 causes acute and severe respiratory distress in the infected host. The virus attacks angiotensin-converting enzyme II receptors, leading to COVID-connected pneumonia. Insult to the nervous system can result in acute myocardial injury that permanently impairs the cardiovascular system. 1 The muscular structure of the heart can become inflamed in a condition known as ....
2Centro di Ricerca E. Menni, Fondazione Poliambulanza-Istituto Ospedaliero, Brescia, Italy 3Pluristem Ltd., Haifa, Israel 4Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS, Rome, Italy The COVID-19 pandemic has become a priority in the health systems of all nations worldwide. In fact, there are currently no specific drugs or preventive treatments such as vaccines. The numerous therapies available today aim to counteract the symptoms caused by the viral infection that in some subjects can evolve causing acute respiratory distress syndromes (ARDS) with consequent admission to intensive care unit. The exacerbated response of the immune system, through cytokine storm, causes extensive damage to the lung tissue, with the formation of edema, fibrotic tissues and susceptibility to opportunistic infections. The inflammatory picture is also aggravated by disseminated intravascular coagulation which worsens the damage not only to the respiratory system, but also ....