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Multipoint Analysis in Biological Production by Process Mass Spectrometry


Multipoint Analysis in Biological Production by Process Mass Spectrometry
In recent years, the utilization of online process analytical technology (PAT) has become a high-profile endeavor in the biotechnology industry.
Since the early 1980s, a number of fermentation scientists have employed Thermo Scientific™ Process Mass Spectrometers to reliably monitor the composition of gas streams into and out of bioreactors and fermenters.
When making the first steps towards process control, it is not uncommon for some to think that the measurement of carbon dioxide and oxygen in the effluent is all that is needed and that sufficient accuracy can be acquired by discrete measurement technology. Both of these assumptions are incorrect. ....

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