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Pharvaris (PHVS) Announces Positive Top-line Phase 2 Data from the CHAPTER-1 Study of Deucrictibant for the Prophylactic Treatment of HAE Attacks

Pharvaris (PHVS) Announces Positive Top-line Phase 2 Data from the CHAPTER-1 Study of Deucrictibant for the Prophylactic Treatment of HAE Attacks
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Peng Lu , Marca Riedl , Berndt Modig , Clinical Service , University Of California San Diego , Angioedema Center , Us Hereditary Angioedema Association , Office Of Pharvaris , Study Design , Clinical Director , Angioedema Association , California San Diego , Clinical Service Chief , Chief Medical Officer , Chief Executive Office ,

Pharvaris Announces Positive Top-line Phase 2 Data from the

Pharvaris Announces Positive Top-line Phase 2 Data from the
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Berndt Modig , Marca Riedl , Peng Lu , Office Of Pharvaris , Us Hereditary Angioedema Association , Angioedema Center , University Of California San Diego , Clinical Service , Study Design , Clinical Director , Angioedema Association , California San Diego , Clinical Service Chief , Chief Medical Officer , Chief Executive Office ,

Pharvaris Announces Positive Top-line Phase 2 Data from the CHAPTER-1 Study of Deucrictibant for the Prophylactic Treatment of HAE Attacks

Primary endpoint met: deucrictibant significantly reduced attack rate The primary endpoint of the CHAPTER-1 study measured the time-normalized number of investigator-confirmed HAE attacks during the treatment period. The monthly attack rate was reduced by 84.5% (p=0.0008) compared to placebo in participants who received 40 mg/day of deucrictibant. Primary endpoint met; 40 mg/day orally administered deucrictibant significantly reduced mean monthly attack rate by 84.5% (p=0.0008) compared to place ....

Berndt Modig , Marca Riedl , Peng Lu , Office Of Pharvaris , Us Hereditary Angioedema Association , Angioedema Center , University Of California San Diego , Clinical Service , Study Design , Clinical Director , Angioedema Association , California San Diego , Clinical Service Chief , Chief Medical Officer , Chief Executive Office , Preventative Treatment , Attack Rate , Primary Endpoint , Clinical Study , Treatment Period ,