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 E-Mail A new approach to tackling viruses by targeting the control centre in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defence against future pandemics, according to new research at the University of Birmingham. In a new study, published in Angewandte Chemie, researchers have shown how this approach could be effective against the SARS-CoV-2 virus responsible for the COVID-19 pandemic. Earlier modelling and in vitro analysis by the team and published in Chemical Science has also shown effectiveness against the HIV virus. Professor Mike Hannon, from the University of Birmingham s School of Chemistry, is co-lead author of the study. He said: Although SARS-CoV-2 vaccines have been developed with unprecedented speed, there has still been a 12-month wait for development and approval. Viral pandemics remain a big threat and so broad-spectrum anti-virals are urgently needed to keep diseases like coronaviruses at bay while effective dru

United kingdomPawel grzechnikMike hannonAngewandte chemieUniversity of birmingham school chemistryRoyal societyUnited kingdom researchUniversity of birmingham enterpriseUniversity of birmingham school biosciencesUniversity of birminghamSciences research councilUniversity of birmingham institute immunologyResearch foundationChemical scienceZania stamatakiPhysical sciences research council