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What do we know about covid in immunocompromised people?

Katharine Lang looks at the continuing dangers of covid for immunocompromised people, the treatments available to them, and how antivirals such as remdesivir may help

### Is covid still a particular risk for people who are immunocompromised?

Although the morbidity and mortality of covid-19 have reduced drastically in highly vaccinated and highly previously exposed populations, the disease is still a threat to the lives of more vulnerable people, particularly those without a functioning immune system. They are the people at “greatest risk,” says Bill Schaffner, professor of preventive medicine and infectious diseases at Vanderbilt University in Nashville, Tennessee.

Around 12 000 people died of covid-19 worldwide from 1 to 28 May 2023, show data from the World Health Organization. Schaffner says that the patients who are dying are mainly immunocompromised people who are older and therefore have weaker immune systems or have underlying conditions such as cancer ....

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