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Novel nanotech improves cystic fibrosis antibiotic by 100,000-fold


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IMAGE: After four hours, if the infection is not treated it kills all the cells (line 1); Unformulated tobramycin keeps the cells alive, but it does not eradicate the infection (line.
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Credit: UniSA
World-first nanotechnology developed by the University of South Australia could change the lives of thousands of people living with cystic fibrosis (CF) as groundbreaking research shows it can improve the effectiveness of the CF antibiotic Tobramycin, increasing its efficacy by up to 100,000-fold.
The new technology uses a biomimetic nanostructured material to augment Tobramycin - the antibiotic prescribed to treat chronic Pseudomonas aeruginosa lung infections in severe cases of CF - eradicating the infection in as little as two doses. ....

University Of South Australia , South Australia , Annabel Mansfield , Clive Prestidge , Nicky Thomas , Helmholtz Institute For Pharmaceutical Research Saarland , Saarland University , Basil Hetzel Institute For Translational Health , Unisa Cancer Research Institute , Centre For Excellence , Professor Clive Prestidge , Chelsea Thorn , Basil Hetzel Institute , Translational Health , Bio Nano Science , Biofilm Test , Research Institute , Helmholtz Institute , Pharmaceutical Research Saarland , பல்கலைக்கழகம் ஆஃப் தெற்கு ஆஸ்திரேலியா , தெற்கு ஆஸ்திரேலியா , அன்னாபெல் மேன்ஸ்ஃபீல்ட் , நிக்கி தாமஸ் , உனஇச புற்றுநோய் ஆராய்ச்சி நிறுவனம் , மையம் க்கு சிறப்பானது , செல்சியா முள் ,