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Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR)

Objective To investigate the effectiveness of combining mirtazapine with serotonin-noradrenaline reuptake inhibitor (SNRI) or selective serotonin reuptake inhibitor (SSRI) antidepressants for treatment resistant depression in primary care.

Design Two parallel group multicentre phase III randomised placebo controlled trial.

Setting 106 general practices in four UK sites; Bristol, Exeter, Hull, and Keele/North Staffs, August 2013 to October 2015.

Participants 480 adults aged 18 or more years who scored 14 or more on the Beck depression inventory, second revision, fulfilled ICD-10 (international classification of diseases, 10th revision) criteria for depression, and had used an SSRI or SNRI for at least six weeks but were still depressed. 241 were randomised to mirtazapine and 239 to placebo, both given in addition to usual SSRI or SNRI treatment. Participants were stratified by centre and minimised by baseline Beck depression inventory score, sex, and current psychol ....

United Kingdom , Caroline Jenkinson , Mary Carter , Ianm Anderson , Dalan Montgomery , Marie Platt , Davids Kessler , Stephaniej Macneill , William Hollingworth , Simon Davies , John Campbell , Sue Jones , Una Macleod , Glyn Lewis , Tom Shepherd , Timj Peters , Helen Gibson , Alison Burns , Deborah Tallon , Simon Gilbody , Chrism Dickens , Ellie Kingsland , National Institute For Health Research , National Health Service , Health Technology Assessment , Biomedical Research Centre At University Hospitals Bristol ,

New online medicine summer school to inspire Hull doctors of the future

New online medicine summer school to inspire Hull doctors of the future
hulldailymail.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from hulldailymail.co.uk Daily Mail and Mail on Sunday newspapers.

Astrazeneca Covid , Una Macleod , Daisy Metcalfe , Paul Whybrow , Hull York Medical School , Schools Council , University Of Hull , Summer School , Gateway Year Programme , School Pathways To Medicine , Health Education England , School University Of Hull , Medical Schools Council , Medical School , Health Education ,

York researchers collaborate in 'most important health study in generation'

In a groundbreaking new health study, a team of researchers will capture the journeys of 30,000 Bradford schoolchildren from adolescence to adulthood ....

United Kingdom , Simon Gilbody , Kate Pickett , Una Macleod , Matthias Ruth , John Wright , Dean Of Hull York Medical School , Hull York Medical School , Bradford City Centre University Of York , University Of York , Bradford Institute For Health Research , Department Of Health Sciences , City Centre , Bradford Institute , Health Research , Health Sciences , Professor John Wright , Pro Vice Chancellor ,

University of York: York researchers collaborate in the 'most important health study in a generation' – India Education | Latest Education News | Global Educational News

Researchers from the University of York and Hull York Medical School will work in partnership with the Bradford Institute for Health Research (BIHR) on the new seven-year project, which has secured £7m in funding from the Wellcome Trust.Known as Age ....

United Kingdom , Simon Gilbody , Kate Pickett , Una Macleod , Matthias Ruth , John Wright , Dean Of Hull York Medical School , Hull York Medical School , University Of York , Bradford Institute For Health Research , Department Of Health Sciences , Bradford Institute , Health Research , Health Sciences , Professor John Wright , Pro Vice Chancellor ,

'Much-needed' footpath and bus stop open on busy Skye road

'Much-needed' footpath and bus stop open on busy Skye road
pressandjournal.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pressandjournal.co.uk Daily Mail and Mail on Sunday newspapers.

United Kingdom , Bob Bruce , Una Macleod , Catriona Coghill , Callum Munro , John Finlayson , Sligachan Hotel , Bear Scotland , ஒன்றுபட்டது கிஂக்டம் , பாப் காயங்கள் , ஊன மக்ல்ந்ட் , காலம் மன்ரோ , ஜான் ஃபின்லேசன் , தாங்க ஸ்காட்லாந்து ,