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Two Deaths From Liver Failure Linked to Spinal Muscular Atrophy Drug

Two children have died 5-6 weeks after infusion with the gene therapy drug onasemnogene abeparvovec (Zolgensma), a treatment for spinal muscular atrophy, its manufacturer reports. ....

United States , Drug Administration , Medscape Medical News , Muscular Atrophy , Uscular Atrophies , Acute Hepatic Failure , Acute Liver Failure , Fulminant Liver Failure , Ulminant Hepatic Failure , Gene Therapy , Genomic Medicine , Edicine Genomic , Liver Failure , Hepatic Failure , Precision Medicine , Spinal Muscular Atrophy , Spinal Muscle Atrophy , Patient Safety , Adverse Effects , Side Effects ,

Cidofovir for Adenovirus-Related Hepatitis in Kids Clears Viremia

Off-label use of cidofovir in children with acute liver failure and confirmed adenovirus infection cleared the virus or substantially reduced viremia in a small case series from London. ....

City Of , United Kingdom , Savita Verma , Reuters Health , Kings College Hospital , Lancet Gastroenterology , Biliary Disease , Allbladder Disease , Transplantation Of The Liver , Epatic Transplantation , Liver Transplantation , Acute Hepatic Failure , Acute Liver Failure , Fulminant Liver Failure , Ulminant Hepatic Failure , Viral Hepatitis , Covid 19 , 019 Novel Coronavirus , 019 Ncov , Uhan Coronavirus , Uman Coronavirus Hku1 ,

CDC Updates Guidelines for Hepatitis Outbreak Among Children

Unexplained hepatitis cases have been reported in children worldwide, reaching 450 cases and 11 deaths, according to the latest update from the European Centre for Disease Prevention and Control. ....

United States , United Kingdom , Philippa Easterbrook , European Union , European Centre For Disease Prevention , European Centre , Disease Prevention , Viral Hepatitis , Viral Illness , Liver Disease , Infection Control , Transplantation Liver , Epatic Transplantation , Ransplantation Hepatic , Liver Transplantation , Acute Hepatic Failure , Acute Liver Failure , Fulminant Liver Failure , Ulminant Hepatic Failure , 019 Novel Coronavirus , 019 Ncov ,

Label Changes Did Not Cut Accidental Acetaminophen Overdoses

Although acetaminophen is safe at therapeutic doses, overdose entails a risk for acute liver failure. Clinicians should review patients OTC medications, said the researchers. ....

United States , United Kingdom , Tony Antoniou , Susane Farrell , University Of Toronto , Health Canada , Harvard Medical School , Canadian Medical Association Journal , Department Of Emergency Medicine , Canadian Institute For Health Information , Canadian Medical Association , Liver Failure , Canadian Institute , Health Information , Medscape Medical News , Emergency Medicine , Rug Overdose , Over The Counter Otc Non Prescription , Acute Hepatic Failure , Acute Liver Failure , Fulminant Liver Failure , Ulminant Hepatic Failure , Hepatic Failure , Inpatient Care , Wound Management , Medical Literature ,

Human CRP Protects Against Acetaminophen-Induced Liver Injury

The hepatocyte-produced inflammatory marker C-reactive protein may be a checkpoint that protects against acetaminophen-induced acute liver injury, according to research findings. ....

Hai Yun Li , Xian Jiaotong University In Shaanxi , Xi An Jiaotong University , Molecular Gastroenterology , C Reactive Protein , Liver Trauma , Rauma To The Liver , Rug Overdose , Iological Marker , Acute Hepatic Failure , Acute Liver Failure , Fulminant Liver Failure , Ulminant Hepatic Failure , Adverse Effects , Side Effects , Patient Safety , Anti Inflammatory Agents , Intravenous Iv ,