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Study finds how intrinsically disordered proteins guard genome

The protection and preservation of the genetic material by tiny holes in the cell nucleus is crucial for healthy ageing. German researchers from the Synthetic Biophysics of Protein Disorder Group at Johannes Gutenberg University Mainz and the Department of Theoretical Biophysics at the Max Planck Institute of Biophysics in Frankfurt am Main have literally filled a gap in our knowledge of the composition and operation of these nuclear pores. ....

Gerhard Hummer , Edward Lemke , Martin Beck , Max Planck Institute Of Biophysics , Institute Of Molecular Biology Mainz , Department Of Theoretical Biophysics , Synthetic Biophysics , Protein Disorder Group , Johannes Gutenberg University Mainz , Theoretical Biophysics , Max Planck Institute , Adjunct Director , Molecular Biology Mainz , Uard Genome , Healthy Aging , Uclear Pores , Na Damaging Substances , Intrinsically Disordered Proteins ,