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Novel HER2 Assay to Predict HER2+ Breast Cancer Tx Response

An award-winning genomic assay for measuring HER2 mRNA expression could help predict treatment responses in advanced HER2+ breast cancer and ultimately guide clinical decision-making, suggests study. ....

United States , Emory University , Comunidad Autonoma De Cataluna , Sunil Badve , Aleix Prat , Department Of Pathology , Laboratory Medicine , Pii Sunyer Biomedical Research Institute , Journal Of The National Cancer Institute On , Reveal Genomics , Translational Genomic , Targeted Therapies , Solid Tumors , Sunyer Biomedical Research Institute , National Cancer Institute , Medscape Medical News , Breast Cancer , Alignant Breast Neoplasm , Biologic Therapy , Metastatic Breast Carcinoma , Genomic Medicine , Edicine Genomic , Antineoplastic Drug , Nti Cancer Agents , Alignant Neoplasia , Malignant Head And Neck Neoplasm ,

Mastocytosis: Rare, Underdiagnosed, Potentially Fatal

Systemic mastocytosis is widely underdiagnosed, and many more hematologic oncologists should be looking for it, say experts. ....

New York , United States , El Paso , San Antonio , University Of Texas , Attilio Orazi , Ruben Mesa , University Of Texas Health , International Consensus Classification Of Myeloid Neoplasms , Drug Administration , Leukemia Myeloma Congress , World Health Organization Classification Of Tumours , American Society Of Hematology , Stanford Calif Cancer Institute Jason Gotlib , University Of Chicago , Texas Tech University , Cancer Institute , Jason Gotlib , Myeloma Congress , World Health Organization Classification , Blue Book , International Consensus Classification , Myeloid Neoplasms , Acute Leukemias , Texas Health , Blueprint Medicines ,

Thyroid Hormone Reference Range May Not Apply for Cancer Patients

Normal reference ranges of blood levels of thyroid-stimulating hormone and free thyroxine may not be suitable to determine thyroid function in patients with various types of cancer. ....

Ohio State University , Research Square , Thyroid Disorder , Breast Cancer , Alignant Breast Neoplasm , Thyroid Cancer , Thyroid Carcinoma , Ancer Of The Thyroid , Alignant Neoplasia , Biologic Therapy , Tyrosine Kinase Inhibitor ,

Immune-Related Biomarkers Can Help Guide HER2+ Breast Cancer Tx

Immune-related gene expression signatures can predict pathologic complete response and could be used to help decide which HER2 therapies to use for which patients, say researchers. ....

United States , Dana Farber Cancer Institute , Lisa Anne Carey , Lineberger Comprehensive Cancer Center , Leukemia Group , University Of North Carolina At Chapel Hill , North Carolina , Paolo Tarantino , Medscape Medical , Breast Cancer , Alignant Breast Neoplasm , Biologic Therapy , Antineoplastic Drug , Nti Cancer Agents , Alignant Neoplasia , Humanized Monoclonal Antibody , Polymerase Chain Reaction , Iological Marker ,

Tucatinib Plus Trastuzumab Approved for HER2+ CRC

The combination of HER2-targeted agents is already approved for use in breast cancer and is now is the first treatment approved for HER2-positive colorectal cancer. ....

John Strickler , Duke University Medical Center , Drug Administration , Colorectal Cancer , Antineoplastic Drug , Nti Cancer Agents , Biologic Therapy , Breast Cancer , Alignant Breast Neoplasm , Alignant Neoplasia , Humanized Monoclonal Antibody , Microsatellite Instability High , Microsatellite Instability High , Micro Satellite Instability High ,