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NYUAD researchers develop high throughput paper-based arrays of 3D tumor models

Credit: NYU Abu Dhabi
Abu Dhabi, UAE, February 22: By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms. With the new paper-based technology, the formed tumor models can be safely cryopreserved and stored for prolonged periods for on-demand drug testing use. These cryopreservable tumor models could provide the pharmaceutical industry with an easy and low cost method for investigating the outcomes of drug efficacy, potentially bolstering personalized medicine. The developed technology can be transferred to other trending therapeutic applications such as measuring tumor response to drug concentration gradients, studying cancer cell signaling pathways, and investigations of invasive tumors. ....

United States , Abu Dhabi , Mohammada Qasaimeh , Principal Investigator Of The Laboratory , Cryopreservable Arrays , Tumor Models , High Throughput Drug Screening , Assistant Professor , Biomedical Engineering , Principal Investigator , Bisan Samara , Paper Based Cell Cryopreservation , Advanced Biosystems , Biomedical Environmental Chemical Engineering , Medicine Health , Pharmaceutical Science , Research Development , ஒன்றுபட்டது மாநிலங்களில் , ப்ரிந்ஸிபல் புலனாய்வாளர் ஆஃப் தி ஆய்வகம் , கட்டி மாதிரிகள் , உதவியாளர் ப்ரொஃபெஸர் , உயிர் மருத்துவ பொறியியல் , ப்ரிந்ஸிபல் புலனாய்வாளர் , பிசன் சமாரா , உயிரி தொழில்நுட்பவியல் , உயிர் மருத்துவ சுற்றுச்சூழல் இரசாயன பொறியியல் ,

Detailed text transcripts for TV channel - DW - 20180221:16:47:00

That it s still at an early stage of research when it comes to organs the outer shape is important but so is the internal structure which is highly complex so getting to the point where it s actually possible to print entire organs poses a huge challenge on organic. to date know full sized functional organs have been printed how other cell breaks does already cell tumor models. to cancer clinics for research purposes. pediatrician i met a can kill or says working with a startup has helped her research. together we develop a three d. tumor model which we can use in pretty clinical trials we can then see which immune cells are able to enter this three d. structure. based on the results that we get with this model we would then decide which immune cells will use in clinical testing the ones we hope can then ....

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