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Speeding new treatments


University of New Mexico Health Sciences Center
A year into the COVID-19 pandemic, mass vaccinations have begun to raise the tantalizing prospect of herd immunity that eventually curtails or halts the spread of SARS-CoV-2. But what if herd immunity is never fully achieved – or if the mutating virus gives rise to hyper-virulent variants that diminish the benefits of vaccination?
Those questions underscore the need for effective treatments for people who continue to fall ill with the coronavirus. While a few existing drugs show some benefit, there’s a pressing need to find new therapeutics.
Led by The University of New Mexico’s Tudor Oprea, MD, PhD, scientists have created a unique tool to help drug researchers quickly identify molecules capable of disarming the virus before it invades human cells or disabling it in the early stages of the infection. ....

United States , Suman Sirimulla , School Of Medicine , Translational Informatics Division , National Center , University Of New Mexico Tudor Oprea , University Of Texas At El Paso , Translational Sciences , New Mexico , Tudor Oprea , Nature Machine Intelligence , Advancing Translational Sciences , New Mexico , University Of New Mexico , University Of Texas , El Paso , Machine Learning , ஒன்றுபட்டது மாநிலங்களில் , பள்ளி ஆஃப் மருந்து , மொழிபெயர்ப்பு தகவல் பிரிவு , தேசிய மையம் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் இல் எல் பாசோ , மொழிபெயர்ப்பு அறிவியல் , புதியது மெக்ஸிகோ , இயற்கை இயந்திரம் உளவுத்துறை , ல் பாசோ ,

New computational tool helps screen molecules for their potential COVID-fighting properties


New computational tool helps screen molecules for their potential COVID-fighting properties
A year into the COVID-19 pandemic, mass vaccinations have begun to raise the tantalizing prospect of herd immunity that eventually curtails or halts the spread of SARS-CoV-2. But what if herd immunity is never fully achieved - or if the mutating virus gives rise to hyper-virulent variants that diminish the benefits of vaccination?
Those questions underscore the need for effective treatments for people who continue to fall ill with the coronavirus. While a few existing drugs show some benefit, there s a pressing need to find new therapeutics.
Led by The University of New Mexico s Tudor Oprea, MD, PhD, scientists have created a unique tool to help drug researchers quickly identify molecules capable of disarming the virus before it invades human cells or disabling it in the early stages of the infection. ....

United States , Suman Sirimulla , Emily Henderson , Tudor Oprea , School Of Medicine , Translational Informatics Division , National Center , University Of New Mexico , University Of New Mexico Tudor Oprea , University Of Texas At El Paso , Translational Sciences , New Mexico , Nature Machine Intelligence , Advancing Translational Sciences , Corona Virus , Drug Repurposing , Machine Learning , Ars Cov 2 , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , பள்ளி ஆஃப் மருந்து , மொழிபெயர்ப்பு தகவல் பிரிவு , தேசிய மையம் , பல்கலைக்கழகம் ஆஃப் புதியது மெக்ஸிகோ , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் இல் எல் பாசோ , மொழிபெயர்ப்பு அறிவியல் ,

Computational Tool Helps Find Molecules With COVID-19-Fighting Properties


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A year into the COVID-19 pandemic, mass vaccinations have begun to raise the tantalizing prospect of herd immunity that eventually curtails or halts the spread of SARS-CoV-2. But what if herd immunity is never fully achieved - or if the mutating virus gives rise to hyper-virulent variants that diminish the benefits of vaccination?
Those questions underscore the need for effective treatments for people who continue to fall ill with the coronavirus. While a few existing drugs show some benefit, there s a pressing need to find new therapeutics.
Led by The University of New Mexico s Tudor Oprea, MD, PhD, scientists have created a unique tool to help drug researchers quickly identify molecules capable of disarming the virus before it invades human cells or disabling it in the early stages of the infection. ....

United States , Nat Mach Intell , Suman Sirimulla , School Of Medicine , Translational Informatics Division , National Center , University Of New Mexico Tudor Oprea , University Of Texas At El Paso , Translational Sciences , New Mexico , Tudor Oprea , Nature Machine Intelligence , Advancing Translational Sciences , Nat Mach , ஒன்றுபட்டது மாநிலங்களில் , நாட் மச் இன்டெல் , பள்ளி ஆஃப் மருந்து , மொழிபெயர்ப்பு தகவல் பிரிவு , தேசிய மையம் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் இல் எல் பாசோ , மொழிபெயர்ப்பு அறிவியல் , புதியது மெக்ஸிகோ , இயற்கை இயந்திரம் உளவுத்துறை ,

Scientists assemble tool for rapid screening of molecules with anti-COVID properties

UTEP and UNM Collaborate on Online Platform to Accelerate COVID-19 Drug Discovery


 EL PASO, Texas –Drug discovery researchers at The University of Texas at El Paso and the University of New Mexico have leveraged their expertise to develop a rapid online tool to accelerate the discovery of drug therapies for SARS-CoV-2, the virus that causes COVID-19.
REDIAL-2020 is an open-source online suite of computational models that will help scientists rapidly screen small molecules for their potential COVID-19-fighting properties. The platform is available as a web application through DrugCentral.org/Redial.
“REDIAL-2020 is a machine learning platform we developed to estimate the activities of drugs for anit-SARS-COV-2 activities,” said Suman Sirimulla, Ph.D., assistant professor of pharmaceutical sciences at UTEP’s School of Pharmacy. “The platform allows scientists from around the world to identify small molecules that can inhibit SARS-CoV-2, in order to develop new drugs or repurpose existing drugs to treat COVID-19.” ....

United States , Tudori Oprea , Suman Sirimulla , Department Of Internal Medicine , National Center , Texas Advanced Computing Center , University Of New Mexico , School Of Pharmacy , University Of Texas At El Paso , Translational Sciences , Us Army Test , University Of Texas At Austin , Translational Informatics Division , New Mexico , Internal Medicine , Nature Machine , Advancing Translational Sciences , Evaluation Command , ஒன்றுபட்டது மாநிலங்களில் , துறை ஆஃப் உள் மருந்து , தேசிய மையம் , பல்கலைக்கழகம் ஆஃப் புதியது மெக்ஸிகோ , பள்ளி ஆஃப் மருந்தகம் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் இல் எல் பாசோ , மொழிபெயர்ப்பு அறிவியல் , எங்களுக்கு இராணுவம் சோதனை ,