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Interleukin-6 signaling mediates cartilage degradation and pain in posttraumatic osteoarthritis in a sex-specific manner

Interleukin-6 signaling mediates cartilage degradation and pain in posttraumatic osteoarthritis in a sex-specific manner
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United States , National Institutes Of Health , National Institute Of Arthritis , Oa Research Society International , Duke University Institutional Animal Care , Bioresource Center , Duke University Anesthesiology Research Fund , Jackson Laboratory , Society International , National Institutes , Use Committee , Alexa Fluor , Scanco United States , Resource Center , Mini Kit , For Western , Trans Blot Turbo Transfer System , Blotting Substrate , Duke Light Microscopy Core Facility , National Institute , Skin Diseases ,

Rising Prevalence of HIV & Contagious Diseases To Drive Sales of Blotting Systems; Market is Predicted to Expand at a CAGR of 5%: Fact.MR Analysis

Rising Prevalence of HIV & Contagious Diseases To Drive Sales of Blotting Systems; Market is Predicted to Expand at a CAGR of 5%: Fact.MR Analysis
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United States , Rockville Pike , Asia Pacific , Us Sales Office , Cell Signaling Technology Inc , Academic Research Institutes , Advansta Inc , Perkinelmer Inc , Quantitative Western Blotting Solutions , Research Solutions , Key Segments Of Blotting Systems Industry Research , Pharma Biotech Companies , Merck Kga , Ge Healthcare , Bio Techne Corporation , Fact Mr Research , Bio Rad Laboratories Inc , Merck Kgaa , Thermo Fisher Scientific Inc , Key Companies , Sample Copy , Specific Research Solutions , Western Blotting Solutions , Aviva Systems Biology , Systems Biology , Bio Rad Laboratories ,

Frontiers | The CD147 Protein Complex Is Involved in Entry of Chikungunya Virus and Related Alphaviruses in Human Cells

2Laboratory for Pharmaceutical Biotechnology, University of Ghent, Ghent, Belgium
3ProGenTomics, Ghent, Belgium
4Laboratory of Proteinscience, Proteomics and Epigenetic Signaling, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium
5Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
Chikungunya virus (CHIKV) is an arbovirus with a global spread and significant public health impact. It is a positive stranded RNA alphavirus belonging to the
Togaviridae family. However, many questions about the replication cycle of CHIKV remain unanswered. The entry process of CHIKV is not completely understood nor are the associated virus-receptor interactions fully identified. Here, we designed an affinity purification mass spectrometry coupled approach that allowed the identification of factors that facilitate entry of CHIKV in human cells. The identified entry factors were further validated using CRISP ....

United States , South Africa , Provence Alpes Côd Azur , Basse Normandie , Krung Thep Mahanakhon , Ubon Ratchathani , Haute Normandie , South African , Mohamed Hussain , Hela Matusali , Indian Ocean , Tatsuo Shioda Mahidol , Feng Zhang , Institute Of Technology , Andres Merits University Of Tartu , Kosaka Center , Research Fund Flanders , Mahidol University , National Collection Of Pathogenic Viruses , West African , Saharan Africa , Modified Eagle , National Collection , Pathogenic Viruses , Lithium Chloride , Streptavidin Sepharose High Performance ,