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Astrocyte Study Ties Vitamin B12 to Multiple Sclerosis Progression

A new study uncovers a molecular connection between vitamin B12 and multiple sclerosis (MS). ....

New York , United States , Tomomi Furihata , Yasuyuki Kihara , Jerold Chun , Richard Rivera , Manisha Ray , Deepa Jonnalagadda , Clayton Ellington , Edwardv Quadros , Hyeon Cheol Lee Okada , Susan Gammon , Takehiko Yokomizo , Arjun Saha , Sanford Burnham Prebys , Scientist Training Program , Human Frontier Science Program , Juntendo University , Life Sciences , National Institute Of Neurological Disorders , Uehara Memorial Foundation , National Institutes Of Health , Tokyo University Of Pharmacy , Mochida Memorial Foundation For , University Of New York , University Of Southern California ,

Link Discovered Between Vitamin B12 Loss, Multiple Sclerosis

Link Discovered Between Vitamin B12 Loss, Multiple Sclerosis
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

New York , United States , Jerold Chun , Deepa Jonnalagadda , Manisha Ray , Arjun Saha , Richard Rivera , Clayton Ellington , Edwardv Quadros , Sanford Burnham Prebys , Tomomi Furihata , Takehiko Yokomizo , Yasuyuki Kihara , Hyeon Cheol Lee Okada , Juntendo University , Mochida Memorial Foundation For , Uehara Memorial Foundation , University Of Southern California , University Of New York , National Institutes Of Health , Scientist Training Program , Tokyo University Of Pharmacy , Human Frontier Science Program , National Institute Of Neurological Disorders , Life Sciences , Cell Reports ,

Intracranial Intrigue: Unmasking the Mutant Genes Behind Brain Aneurysms

Researchers at the RIKEN Center for Brain Science (CBS) in Japan have discovered a set of related mutations that lead to intracranial aneurysms weakened blood vessels in the brain that can burst at any time. The mutations all appear to act on the same biological signaling pathway, and the researcher ....

Xiaoning Sun , Masato Nakafuku , Motoo Nagane , Atsuko Nakanishi Ozeki , Nobuhito Saito , Tadafumi Kato , Hiroyasu Kamiyama , Masashi Fujita , Rokuya Tanikawa , Nakao Ota , Shigeo Okabe , Yoichiro Kamatani , Tomomi Furihata , Hiroyuki Kamiguchi , Koichi Matsuda , Kosumo Noda , Junji Shibahara , Kenjiro Kosaki , Yasuyuki Shima , Hirofumi Nakatomi , Rieko Oyama , Hirochika Kawakami , Hiroki Kurihara , Nobuko Mataga , Satoru Takahashi , Toru Tanaka ,

Stroke of Luck: Therapeutic Target Discovered in Blood–Brain Barrier

Scientists from Japan and the United States have identified a new mechanism of blood-brain barrier degradation in the post-stroke brain, involving acrolein-induced modifications of proheparanase. This discovery could lead to the production of newer and more effective drugs for stroke-related disorders. Credit: Toubibe from Pixabay
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The blood-brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation. Now, for the first time, researchers have identified how a toxic stroke byproduct, acrolein, could activate the barrier-degrading enzyme proheparanase (proHPSE). The research group has discovered that proHPSE degrades the glycocalyx within the post-stroke brain s blood vessels, providing hope for new and effective therapeutics against post-stroke inflammation. ....

United States , Kazuei Igarashi , Tomomi Furihata , Takehiro Suzuki , Toshihiko Toida , Kyohei Higashi , Naoshi Dohmae , Robertj Linhardt , Tokyo University Of Pharmacy , Amine Pharma Research Institute , Rensselaer Polytechnic Institute , Life Sciences , Tokyo University Of Science , Chiba University , Associate Professor Kyohei Higashi , Tokyo University , Biological Chemistry , Sustainable Resource Science , ஒன்றுபட்டது மாநிலங்களில் , டோக்கியோ பல்கலைக்கழகம் ஆஃப் மருந்தகம் , அமீன் பார்மா ஆராய்ச்சி நிறுவனம் , ரென்சீலர் பாலிடெக்நிக் நிறுவனம் , வாழ்க்கை அறிவியல் , டோக்கியோ பல்கலைக்கழகம் ஆஃப் அறிவியல் , சிபா பல்கலைக்கழகம் , டோக்கியோ பல்கலைக்கழகம் ,

Study reveals a potential target for stroke treatment in blood-brain barrier

Study reveals a potential target for stroke treatment in blood-brain barrier
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

United States , Takehiro Suzuki , Naoshi Dohmae , Emily Henderson , Tomomi Furihata , Kazuei Igarashi , Kyohei Higashi , Toshihiko Toida , Robertj Linhardt , Tokyo University Of Pharmacy , Amine Pharma Research Institute , Rensselaer Polytechnic Institute , Life Sciences , Tokyo University Of Science , Chiba University , Junior Associate Professor , Tokyo University , Biological Chemistry , Sustainable Resource Science , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , டோக்கியோ பல்கலைக்கழகம் ஆஃப் மருந்தகம் , அமீன் பார்மா ஆராய்ச்சி நிறுவனம் , ரென்சீலர் பாலிடெக்நிக் நிறுவனம் , வாழ்க்கை அறிவியல் , டோக்கியோ பல்கலைக்கழகம் ஆஃப் அறிவியல் ,