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Optimizing Afatinib Use: Dosing Strategies and Adverse Event Management

Explore dosing nuances and adverse event management strategies for afatinib in treating EGFR mutant non-small cell lung cancer, reflecting real-world practices and clinical insights. ....

Precision Medicine , Biomarker Testing , Afatinib Use , Dosing Strategies , Adverse Event , Non Small Cell Lung Cancer , Afatinib Dosing , Egfr Mutant Nsclc , Adverse Event Management , Dose Modification , Performance Status , Lung Cancer Treatment , Personalized Medicine , Precision Oncology , Tki Therapy ,

Ponatinib Advances as Frontline Therapy in Ph+ ALL: PhALLCON Study Highlights

Bijal Shah, MD, MS, and Hagop Kantarjian, MD, discuss promising results and regulatory progress for ponatinib in frontline Philadelphia-positive acute lymphoblastic leukemia treatment. ....

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First Report of PhALLCON: A Phase 3 Study Comparing Ponatinib vs Imatinib in Newly Diagnosed Ph+ ALL

Expert Elias Jabbour, MD, reviews clinical data from the PhALLCON study of ponatinib vs imatinib in patients with Ph+ acute lymphocytic leukemia and considers its clinical implications. ....

Elias Jabbour , First Report , Comparing Ponatinib , Newly Diagnosed , Acute Lymphocytic Leukemia , Call Cancer , All Leukemia , Ph Positive , Oph All , Tyrosine Kinase Inhibitors , Tki Therapy , Combination Therapy , Bcr Abl , Ponatinib Dose , Ponatinib Dosing , Complete Response , Survival Data , Adverse Events , Drug Adverse Event , Mrd Negativity , Mrd Negative , Duration Of Response , Crossover Therapy , Sequencing Therapy , Event Free Survival , Efs Data ,

Novel Combination Strategies in mCRC: The STELLAR-303 and SUNLIGHT Trials

Before closing out their review of combination therapy in metastatic colorectal cancer, panelists discuss the STELLAR-303 and SUNLIGHT clinical trials. ....

Metastatic Colorectal Cancer With , Positive Disease , Combination Strategies , Colorectal Cancer , Metastatic Crc , Immune Checkpoint Inhibitors , Tki Therapy , Tyrosine Kinase Inhibitors , Stellar 303 , Sunlight Trial , Combination Therapy ,

Combination IO/TKI Strategies in Metastatic Colorectal Cancer

A comprehensive review on combination strategies with immune checkpoint and tyrosine kinase inhibitors in patients with metastatic colorectal cancer. ....

Metastatic Colorectal Cancer With , Positive Disease , Metastatic Colorectal Cancer , Colorectal Cancer , Metastatic Crc , Immune Checkpoint Inhibitors , Tki Therapy , Tyrosine Kinase Inhibitors , Leap 005 , Leap 017 , Cosmic 021 , Combination Therapy ,