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Coronary Sinus Reducer an Option for Intractable Angina?

A coronary sinus reducer met one of two primary endpoints by reducing refractory angina in the ORBITA-COSMIC trial, but not the second, improvement in perfusion.

City ofUnited kingdomUnited statesNorth carolinaDuke universityMichaelj foleyJennifera rymerTimothyd henryRashak al lameeAmerican college of cardiologyResearch at christ hospitalImperial college healthcareLindner centerCanadian cardiovascular societyImperial college londonDuke university school of medicine

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure
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United kingdomNorth carolinaUnited statesPais vascoUniversity of north carolinaCity ofResearch triangle parkR jude samulskiRogerj hajjarChristian rommelPhil mcnamaraJosh griegerTimothyd henryHead of researchSpanish agency for medicinesAsklepios biopharmaceutical inc

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure

AB-1002 is an investigational gene therapy for the treatment of adults with non-ischemic cardiomyopathy and New York Heart Association (NYHA) Class III heart failure symptoms1GenePHIT is a clinical trial to evaluate the safety and efficacy of the one-time administration of AB-1002 and will include the largest number.

University of north carolinaNorth carolinaUnited statesResearch triangle parkCity ofUnited kingdomPais vascoRogerj hajjarJosh griegerPhil mcnamaraR jude samulskiChristian rommelTimothyd henrySteering committee memberTrademark officeManufacturing organization

First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure Treatment

Bayer AG and Asklepios BioPharmaceutical, Inc. (AskBio), a subsidiary of Bayer AG, have announced that the first patient has been randomized in GenePHIT (Gene PHosphatase Inhibition Therapy), a Phase II trial of AB-1002, also known as NAN-101, for the treatment of congestive heart failure (CHF).

United statesTimothyd henryChristian rommelRogerj hajjarHead of researchAmerican heart association scientific sessionsYork heart associationBayer agAsklepios biopharmaceutical incSteering committee memberAsklepios biopharmaceuticalInhibition therapyNew york heart associationPrincipal investigatorSteering committeeHeart failure awareness week

First Patient Randomized In Askbio Phase II Gene Therapy Trial For Congestive Heart Failure

First Patient Randomized In Askbio Phase II Gene Therapy Trial For Congestive Heart Failure
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University of north carolinaNorth carolinaUnited statesPais vascoResearch triangle parkUnited kingdomCity ofChristian rommelAnn pentecost bayerTimothyd henryR jude samulskiRogerj hajjarJosh griegerPhil mcnamara askbioSpanish agency for medicinesTechnology park