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Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants

Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants
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United States , South Africa , Jun Zhang , Tianshu Xiao , Yongfei Cai , Bing Chen , National Institutes Of Health , Massachusetts Consortium On Pathogen Readiness , Boston Children , Molecular Medicine , Emergent Ventures , Massachusetts Consortium , Pathogen Readiness , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , ஜூன் ஜாங் , பிங் சென் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , மாசசூசெட்ஸ் கூட்டமைப்பு ஆன் நோய்க்கிருமி ரெடிநெஸ் , போஸ்டன் குழந்தைகள் , மூலக்கூறு மருந்து , வெளிப்படுகிறது முயற்சிகள் , மாசசூசெட்ஸ் கூட்டமைப்பு , நோய்க்கிருமி ரெடிநெஸ் , தேசிய நிறுவனங்கள் ,

A sturdier spike protein explains the faster spread of coronavirus variants

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IMAGE: This model shows the structure of the spike protein in its closed configuration, in its original D614 form (left) and its mutant form (G614). In the mutant spike protein, the.
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Credit: Bing Chen, PhD, Boston Children s Hospital
BOSTON - March 16, 2021 - The fast-spreading UK, South Africa, and Brazil coronavirus variants are raising both concerns and questions about whether COVID-19 vaccines will protect against them. New work led by Bing Chen, PhD, at Boston Children s Hospital analyzed how the structure of the coronavirus spike proteins changes with the D614G mutation carried by all three variants and showed why these variants are able to spread more quickly. The team reports its findings in ....

United States , South Africa , United Kingdom , Jun Zhang , Hanqin Peng , Piotr Sliz , Haisun Zhu , Yongfei Cai , Bing Chen , Alec Woosley , Richard Walsh Jr , Tianshu Xiao , Jianming Lu , Structural Biology Harvard Medical School , National Institutes Of Health , Harvard Center , Boston Children Division Of Molecular Medicine , Codex Biosolutions Inc , Boston Children , Nature Structural , Molecular Biology , Molecular Medicine , Sophia Rits Volloch , Codex Biosolutions , Sarah Sterling , Richard Walsh ,