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Mission: The mission of Human Brain Collection Core (HBCC) is to learn about the causes and mechanisms of mental illnesses, which are brain diseases. To be able to conduct this research, we obtain brains from deceased individuals with and without mental illness. The results will help scientists develop new therapies and preventive strategies. Sources of Donated Brains: We obtain brains through the Offices of the Chief Medical Examiner (OCMEs) of Virginia and the District of Columbia. Our personnel are notified of potential donations by OCMEs. We then contact the next-of-kin of the decedent to obtain consent for donation of the entire brain and a blood sample. Our personnel audiotape the next-of-kin’s consent as an official record of the donation. Only after obtaining consent, we arrange with the OCMEs to collect the tissues. There is no cost to the next-of-kin or the decedent’s family. There is no direct benefit to the family for allowing the donation. The donat ....