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AC Immune's Targeted Anti-pTau Active Immunotherapy for Alzheimer's Disease Advances into Phase 2b Trial

AC Immune’s Targeted Anti-pTau Active Immunotherapy for Alzheimer’s Disease Advances into Phase 2b Trial Potentially registration-enabling Phase 2b study (ReTain) will evaluate the effect of ACI-35.030 on cognition and Tau pathology in approximately 500 participants with preclinical Alzheimer’s disease (AD)Anti-pTau active immunotherapy being designed to potentially prevent or reduce cognitive decline could address need of over 315 million people globally1 with preclinical ADAC Immune to receive ....

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Alzheimer's Disease is a More Heterogeneous Condition Than Previously Considered


Alzheimer’s Disease is a More Heterogeneous Condition Than Previously Considered
by Karishma Abhishek on 
May 3, 2021 at 11:22 PM
Lund University, as published in the journal
Nature Medicine.
Alzheimer s disease (AD) is a
neurodegenerative disease that leads to gradual memory loss and behavioral changes. It is characterized by the formation of beta-amyloid plaques and the tau proteins in the brain tissues, years before the actual symptoms occur.
The progression of this abnormal tau protein accumulation in the brain is a key marker for Alzheimer s. With the aid of an advanced medical imaging technique - PET technology, monitoring of toxic protein accumulation in the brain has become possible in recent times. ....

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