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Down Syndrome, Like Alzheimer's, Is a Double-Prion Disorder

The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer’s disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study shows that these tangles and plaques are driven by the same amyloid beta (Aß) and tau prions as Alzheimer’s disease. ....

United States , Erika Castillo , Tatsushi Aoyagi , Stanley Prusiner , William Seeley , Carlo Condello , Alison Maxwell , Proceedings Of The National Academy Sciences , Institute For Neurodegenerative Diseases , National Institute On , Department Of Pharmaceutical Chemistry , Weill Institute For Neurosciences , National Institute , National Academy , Nobel Prize , Brains Give , Neurodegenerative Diseases , Insights Could Lead , Pharmaceutical Chemistry ,