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Dr. John Stagg, A World-Leader in the Adenosine Pathway, Joins Scientific Advisory Board of Tarus Therapeutics, Inc.

Dr. John Stagg, A World-Leader in the Adenosine Pathway, Joins Scientific Advisory Board of Tarus Therapeutics, Inc.
phoenixherald.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phoenixherald.com Daily Mail and Mail on Sunday newspapers.

Sushant Kumar , John Stagg , Markj Smyth , Peter Maccallum Cancer Center , Cancer Institute Of Montreal , Faculty Of Pharmacy At University Montreal , Tarus Therapeutics Inc , Mcgill University , Centre Hospitalier , Professor John Stagg , Taru Scientific Advisory Board , Senior Advisor , Cancer Institute , Professor Mark , Scientific Advisory Board , Tarus Therapeutics , Scientific Advisory Board ,

Dr. John Stagg, A World-Leader in the Adenosine Pathway, Joins Scientific Advisory Board of Tarus Therapeutics, Inc.

Dr. John Stagg, A World-Leader in the Adenosine Pathway, Joins Scientific Advisory Board of Tarus Therapeutics, Inc.
pittsburghstar.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pittsburghstar.com Daily Mail and Mail on Sunday newspapers.

Sushant Kumar , John Stagg , Markj Smyth , Peter Maccallum Cancer Center , Cancer Institute Of Montreal , Faculty Of Pharmacy At University Montreal , Tarus Therapeutics Inc , Mcgill University , Centre Hospitalier , Professor John Stagg , Taru Scientific Advisory Board , Senior Advisor , Cancer Institute , Professor Mark , Scientific Advisory Board , Tarus Therapeutics , Scientific Advisory Board ,

Tarus Therapeutics receives clearance from the FDA to initiate clinical trial of TT-4 (A2BR antagonist) in cancer patients


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NEW YORK, NY / ACCESSWIRE / May 27, 2021 / Tarus Therapeutics Inc., an innovative biotechnology company developing adenosine receptor antagonists for cancer immunotherapy, today announced that it has received clearance from the US Food and Drug Administration (FDA) for its Investigational New Drug (IND) application to proceed with a clinical study of TT-4, an oral small molecule drug targeting the Adenosine A2B receptor (A2BR).
Tarus plans to initiate a Phase 1a/1b study in the third quarter of 2021 to evaluate TT-4 in patients with advanced solid tumors both as a monotherapy and in combination with other anti-cancer agents.
Adenosine signaling is not only immunosuppressive but also directly promotes tumor growth and metastasis. A2BR biology is distinct from A2AR in that its expression is induced by hypoxia via HIF1 (hypoxia-inducible factor), leading to the activation of transcription factors such as ERK, JNK and p38 MAPK in tumor cells. This cascade in turn has b ....

Kostenloser Wertpapierhandel , Sushant Kumar , Tarus Therapeutics Inc , Drug Administration , Investigational New Drug , Chief Executive Officer , Tarus Therapeutics , சுஷாந்த் குமார் , தலைமை நிர்வாகி அதிகாரி ,

Tarus Therapeutics Receives Clearance From the FDA To Initiate Clinical Trial of TT-10 (A2AR Antagonist) in Cancer Patients


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NEW YORK, NY / ACCESSWIRE / April 6, 2021 / Tarus Therapeutics Inc., an innovative biotechnology company developing adenosine receptor antagonists for cancer immunotherapy, today announced that it has received clearance from the US Food and Drug Administration (FDA) for its Investigational New Drug (IND) application to proceed with a clinical study of TT-10, an oral small molecule drug targeting the Adenosine A2A receptor (A2AR).
Tarus plans to initiate a Phase 1a/1b study in the third quarter of 2021 to evaluate TT-10 in patients with advanced solid tumors both as a monotherapy and in combination with other anti-cancer agents.
This IND clearance is a key milestone for Tarus as we continue to advance our portfolio of adenosine receptor antagonists for cancer immunotherapy. We are pleased to be entering the clinic with our potentially best-in-class A2AR antagonist, said Sushant Kumar, Ph.D., Chief Executive Officer, Tarus Therapeutics. This is a very exciting mom ....

Kostenloser Wertpapierhandel , Sushant Kumar , Tarus Therapeutics Inc , Drug Administration , Investigational New Drug , Chief Executive Officer , சுஷாந்த் குமார் , தலைமை நிர்வாகி அதிகாரி ,