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Harnessing proteogenomics in the quest for new drug targets


Editorial Article: Harnessing cutting-edge proteogenomics in the quest for novel drug targets
Discover how collaborative research between big pharma and academia is using the latest proteomics platforms to revolutionize drug discovery
10 May 2021
Dr. Anders Mälarstig, Director of Target Sciences at Pfizer Worldwide Research and Development
With the advent of high-throughput multiplexed proteomic technology, the days of the standard pre-clinical disease model in drug discovery might be numbered. As the pharmaceutical industry looks towards more human-based discovery of novel drug targets, the mapping of protein quantitative trait loci (pQTL) is allowing more confident inference of disease causality for a given protein and helping to map how those proteins are regulated. This has the potential to revolutionize the drug discovery process and a major academia-industry consortium is at the forefront of efforts to do just that. ....

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