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Nivolumab Plus Talazoparib Does Not Induce Responses in Heavily Pretreated Melanoma

Nivolumab plus talazoparib did not produce RECIST-based tumor responses in heavily pretreated patients with unresectable or metastatic melanoma. ....

United States , James Isaacs , Department Of Hematology , Medical Oncology , Cleveland Clinic , Cleveland Clinic Gross Family Melanoma Registry , Nivolumab Plus Talazoparib , Aacr Annual Meeting ,

The Role of Combination Therapy in mCRPC

Rashid K. Sayyid, MD, MSc, discusses the role of combination therapy in metastatic castrate-resistant prostate cancer. ....

Prostate Cancer Treatment Landscape , Combination Therapy , Prostate Cancer , Prostate Cancer Treatments , Parp Inhibitors , Metastatic Castrate Resistant Prostate Cancer , Radium 223 ,

#VisualAbstract: Talazoparib plus enzalutamide improves progression-free survival in metastatic prostate cancer

Click to read the study in The Lancet ©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc. ....

Minute Medicine Inc , Prostate Cancer ,

Talazoparib plus enzalutamide improves progression-free survival in metastatic prostate cancer

1. Progression-free survival was significantly higher in the talazoparib plus enzalutamide group compared to enzalutamide alone. 2. There were no treatment-related fatalities among patients in the talazoparib group. Evidence Rating Level: 1 (Excellent) Study Rundown: Prostate cancer is the second most common malignancy among men. Despite existing therapies, metastatic castration-resistant prostate cancer (mCRPC) remains a ....

Rating Level , Metastatic Castration Resistant Prostate , Between Jan , Metastatic Castration Resistant Prostate Cancer , Metastatic Castration Resistant Prostate Cancer Mcrpc , Prostate Cancer , Prostate Cancer Metastasis , Chronic Disease ,

Agarwal Discusses FDA Approval of Talazoparib Plus Enzalutamide in HRR Gene–Mutated mCRPC

Neeraj Agarwal, MD, speaks on the significance of the approval and how the combination of talazoparib and enzalutamide will fit into the treatment landscape of HRR gene–mutated mCRPC. ....

Neeraj Agarwal , Huntsman Cancer Institute , Huntsman Cancer , Prostate Cancer , Hrr Gene Mutated Mcrpc ,