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Orexin receptor 2 agonist reduces symptoms of narcolepsy type 1

1. In this randomized controlled trial, an oral orexin receptor 2 (OX2R) agonist (TAK-994) was associated with improvements in wakefulness, sleepiness, and cataplexy incidence among patients with narcolepsy type 1. 2. TAK-994 was also associated with liver enzyme elevation and drug-induced hepatotoxicity. Evidence Rating Level: 1 (Excellent) Study Rundown: Narcolepsy is a rare chronic disorder ....

Minute Medicine Inc , Rating Level , Wakefulness Test , Epworth Sleepiness Scale , Confidence Interval , Chronic Disease , Narcolepsy Type 1 , Orexin Receptor 2 Agonist , Tak 994 ,

Takeda Provides Pipeline Update and Shares Goal to Increase Revenue 50% by FY2030 at the 39th Annual J.P. Morgan Healthcare Conference

Takeda Pharmaceutical Company Limited
Takeda Provides Pipeline Update and Shares Goal to Increase Revenue 50% by FY2030 at the 39th Annual J.P. Morgan Healthcare Conference
Tuesday, January 12, 2021 3:15PM IST (9:45AM GMT)

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Wave 1 Pipeline Portfolio Includes 12 New Molecular Entities Targeted for Launch by FY2024 Representing Best-in-Class/First-in-Class Therapies with Significant Market Potential
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Rapid Deleveraging On Track to Achieve Target of 2x Net Debt / adjusted EBITDA within Fiscal Years 2021 to 2023

Takeda Pharmaceutical Company Limited
(TSE:4502/NYSE:TAK) (“Takeda”) provided an update on the progress of its continued transformation and growth today at the virtual 39th Annual J.P. Morgan Healthcare Conference. President and Chief Executive Officer, Christophe Weber, shared details on Takeda’s portfolio and pipeline strategy and financial outlook, including key programs expected to contribute to the co ....

United States , Christophe Weber , Holly Campbell , Kazumi Kobayashi , International Financial Reporting Standards , University Of Texas Md Anderson Cancer Center , Us Centers For Medicare Medicaid Services , Takeda Pharmaceutical Company Limited , Drug Administration , Takeda Pharmaceutical Company , Exchange Commission , Japanese Ministry Of Health , Portfolio Includes , Molecular Entities Targeted , First In Class Therapies , Significant Market , Rapid Deleveraging On Track , Achieve Target , Net Debt , Fiscal Years , Pharmaceutical Company Limited , Chief Executive Officer , Breakthrough Therapy , Japanese Ministry , Chinese Food , Assets Have Significant Market ,