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#VisualAbstract: Teplizumab Improves β-cell Function in Newly Diagnosed Type 1 Diabetes

1. In this randomized-controlled trial, two 12-day courses of teplizumab improved C-peptide levels compared to placebo at week 78 in patients with stage three type 1 diabetes. 2. No significant differences were observed between the teplizumab and placebo groups with respect to secondary clinical outcomes, including clinically relevant hypoglycemic events. Evidence Rating Level: 1 (Excellent) Study ....

Beta Cell , Beta Cell Function , Type 1 Diabetes ,

When Uncontrolled Diabetes and a Fungus Meet: Emergency Treatment of Rhino-Orbital-Cerebral Mucormycosis

JAMA used a case report of rhino-orbital-cerebral mucormycosis in a patient with uncontrolled diabetes to demonstrate correct and incorrect treatment choices. ....

Vitalii Vodolazskyi , Yale School Of Medicine , Yale School , Image Credit , Clinical Challenge , Type 1 Diabetes ,

Camilla Levister on the Nuances of Designing a Pregnancy-Specific Artificial Pancreas System for T1D

Camilla Levister, MS, ANP-C, CDCES, a nurse practitioner at the Icahn School of Medicine at Mount Sinai Hospital in New York, gives insight into the nuances of testing closed-loop insulin delivery systems for pregnant women. ....

New York , United States , Camilla Levister , American Diabetes Association , Icahn School Of Medicine At Mount Sinai , Icahn School , Mount Sinai , Mount Sinai Hospital , Mayo Clinic , Sansum Diabetes , Type 1 Diabetes , T1d And Pregnancy ,