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Renal denervation lowers BP regardless of antihypertensive regimen, polypharmacy burden

Renal denervation lowered blood pressure out to 36 months, regardless of baseline antihypertensive class combinations and polypharmacy burden, according to an analysis of the Global SYMPLICITY Registry DEFINE.At 36 months, 31% of participants decreased the number of antihypertensive drug classes, according to the study published in Hypertension. ....

Felix Mahfoud , Saarland University Medical Center , Adobe Stock , Symplicity Spyral , Symplicity Flex ,

BP Reduction With Renal Denervation Still Evident a Decade On

The new analysis has several limitations, but Deepak Bhatt says it provides reassurances about the durability of the procedure. ....

New York , United States , Deepak Bhatt , Homburg Saar , Hussam Al Ghorani , Saarland University Hospital , Journal Of The American College Cardiology , Drug Administration , Md Saarland University , Symplicity Flex , American College , Saarland University , Icahn School , Mount Sinai , Available Patients , Simplicity Spyral ,

Legacy of Neutral SYMPLICITY HTN-3 Recast by Long-term Outcomes

Although interest in renal denervation in hypertension fell off after disappointing results from the 2014 trial, a new, longer-term analysis argues the treatment may have worked after all. ....

New York , United States , Naomi Fisher , Daiichi Sankyo Eli Lilly , Deepakl Bhatt , Roxana Mehran , Medscape Web , Insel Gruppe , Bristol Myers Squibb , Harvard Medical School , Boston Scientific , Journal Of The American Medical Association , Icahn School Of Medicine At Mount Sinai , Duke University , Transcatheter Cardiovascular Therapeutics , Icahn School , Mount Sinai , New York City , Symplicity Flex , Sham Control , Medscape Cardiology , Abbott Vascular , Eli Lilly , Applied Therapeutics , Concept Medical , Element Science ,

SYMPICITY HTN-3's Late Surprise: Sustained BP Drop at 3 Years Despite Earlier Miss

Experts grappled with how to understand the positive findings given that the trial missed its primary endpoint at 6 months. ....

New York , United States , Salt Lake City , University Of Utah , Naomi Fisher , Ajay Kirtane , Deepak Bhatt , Symplicity Spyral , American College Of Cardiology , Md University Of Utah Health Sciences Center , Presbyterian Columbia University Irving Medical Center , Symplicity Flex , New England Journal , Recor Medical , Utah Health Sciences Center , American College , Grinding Halt , Global Symplicity , Columbia University Irving Medical Center ,

SYMPLICITY HTN-3's Late Surprise: Sustained BP Drop at 3 Years Despite Earlier Miss

Experts grappled with how to understand the positive findings given that the trial missed its primary endpoint at 6 months. ....

New York , United States , Salt Lake City , University Of Utah , Naomi Fisher , Ajay Kirtane , Deepak Bhatt , Symplicity Spyral , American College Of Cardiology , Md University Of Utah Health Sciences Center , Presbyterian Columbia University Irving Medical Center , Symplicity Flex , New England Journal , Recor Medical , Utah Health Sciences Center , American College , Grinding Halt , Global Symplicity , Columbia University Irving Medical Center ,