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The substrate-binding domains of the osmoregulatory ABC importer OpuA physically interact

The substrate-binding domains of the osmoregulatory ABC importer OpuA physically interact
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United States , New York , Nordrhein Westfalen , United Kingdom , Palo Alto , Bellows Falls , Great Britain , Cristina Paulino , Maximator Gmb , Panagiotis Drougkas , Bert Poolman , Jasco Inc , Varian Inc , Gatan Inc , Vitrobot Mark Iv Thermofisher Scientific Inc , Ge Healthcare , Chroma Technology , Thermofisher Scientific Inc , Protein Assay Kit Thermofisher Scientific Inc , Beckman Coulter , Supplementary File , For Opua N , C Terminal His , Maximator Gmbh , Assay Kit , Terrific Broth ,

Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens
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Buenos Aires , Distrito Federal , Pkas Mohanty , Eleni Polatoglou , Trypanosoma Bachmaier , Thomas Carell , Ricardo Biondi , Pkas Canaves , Michaela Smolle , Jena Bioscience , Ligprep Schr , Ralph Heermann , Pkacs Jena Bioscience , Interchim Uptisphere , Transfected Mitat , Life Sciences Munich , Gene Center , Ge Healthcare , Gibbs Free Energy , Omicron Biochemicals Inc , Bb Hydrogen , Protein Data Bank , Structure Activity Relationship , Supplementary Table , Supplementary Movie , Andreas Anger ,

Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein

Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein
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National University Of Singapore , Singapore General , Lok Shee Mei , Shu Bo , Institute Of Structural Biology , Career Development Fund , Career Development Award , Singapore Ministry Of Education , Singapore National Research Foundation , Electron Microscopy Facility At Center , Department Of Biological Science , Electron Microscopy Data Bank , National Medical Research Council Of Singapore , Coomassie Blue , Supplementary Fig , Igel Band , Supplementary File , Supplementary Table , West Nile , Supplementary Figure , Structural Biology , Protein Product , Cryo Electron Microscopy Facility , Bioimaging Science , Biological Science , National University ,

Data-driven, participatory characterization of farmer varieties discloses teff breeding potential under current and future climates

A genomic, climatic, agronomic, and participatory characterization of teff agrobiodiversity shows opportunities and challenges of teff improvement in the face of climate change. ....

Debre Zeit , Binshangul Gumuz , New York , United States , Akaki Oromia , Adet Amhara , Tigray Misraquawi , Addis Abeba , Oromia Misraq Harerge , Debre Zeit Agricultural Research Center , Ethiopian Biodiversity Institute , Amhara Regional Agricultural Research Institute , Ethiopian Highlands , Principal Component Analysis , Pairwise Fst , Least Tigray , East Oromia , Misraq Harerge , West Amhara , Agew Awi , Variant Calling , Moran Eigenvector Map , Panicle Appreciation , Supplementary File , Supplementary Table , Jill Cairn ,

"I have never talked to anyone to free my mind" – challenges surrounding status disclosure to adolescents contribute to their disengagement from HIV care: a qualitative study in western Kenya | BMC Public Health

Adolescents living with HIV (ALHIV, ages 10–19) experience complex barriers to care engagement. Challenges surrounding HIV status disclosure or non-disclosure to adolescents may contribute to adolescent disengagement from HIV care or non-adherence to ART. We performed a qualitative study to investigate the contribution of disclosure challenges to adolescent disengagement from HIV care. This was a qualitative study performed with disengaged ALHIV and their caregivers, and with healthcare workers (HCW) in the Academic Model Providing Access to Healthcare (AMPATH) program in western Kenya. Inclusion criteria for ALHIV were ≥1 visit within the 18 months prior to data collection at one of two clinical sites and nonattendance ≥60 days following their last scheduled appointment. HCW were recruited from 10 clinics. Analysis was conducted by multiple independent coders, and narratives of disclosure and care disengagement were closely interrogated. Overarching themes were ....

Rift Valley , United States , Los Angeles , Indiana University , Centre Or Kitale , Institutional Research , Rafiki Center , Moi University , Institutional Review Board At Indiana University , Moi University College Of Health Sciences , Sociocultural Research Consultants , Ethics Committee , Academic Model Providing Access , Moi Teaching , Referral Hospital , North American , Kitale District Hospital , Moi University College , Health Sciences , Institutional Review Board , Supplementary File ,