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No Biopsy Needed to Accurately Diagnose Celiac Disease in Nearly All Adults Celiac.com Sponsor (A1): Celiac.com Sponsor (A1-m): You ve found your Celiac Tribe! Join our like-minded, private community and share your story, get encouragement and connect with others.
In a potentially game-changing move, new research supports the elimination of biopsy in the diagnosis of most cases of adult celiac disease, in favor of the no-biopsy approach. However, this approach has not yet been widely adopted into clinical practice for diagnosing adults, mainly due to a limited international multi-center data, and testing in groups with low celiac disease rates. New research confirms that most adults do not require a biopsy for a reliable celiac disease diagnosis. A recent study by a team of researchers showed that a 10-fold increase in serum IgA antitissue transglutaminase (tTG) antibody levels has high predictive capacity and diagnostic reliability for detecting s ....