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Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial

Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial
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FFR's Future: Negative Trials Spur Debate Over Technology's Role

Some say it still has a niche, albeit smaller in light of recent studies, but as a means to defer not justify a stent. ....

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Funding the Future: How Industry Support for CV Trials Could Evolve

December 17, 2020
When the 5-year results from the controversial EXCEL trial were published earlier this year, it revived an old and divisive stent-versus-surgery debate but it also rekindled questions about how clinical trials are funded. In addition to concerns over trial endpoints and reporting, some physicians complained that EXCEL and other device trials like it can’t be trusted because of the role of the manufacturer in funding the research.
This story is part of
Envision Change
, an end-of-2020 series imagining a different future for cardiology, medicine, research, and health. SEE ALSO: Transforming Clinical Research, Remaking Medicine, Heroes to Human.
The pros and cons of commercial funding in clinical research are well documented, and endless ink has been spent examining the ties between investigators and sponsors and the impact on clinical trials. But what’s the alternative? In a year when so many other aspects of cardiology practice and rese ....

United States , United Kingdom , City Of , Sukhjinder Nijjer , Richard Kovacs , Juan Granada , Andrew Foy , Khurram Nasir , David Brown , American Heart Association , Biomedical Research Centre At Imperial College London , British Cardiovascular Society , Md Washington University School Of Medicine , British Heart Foundation , Phd Imperial College Healthcare , European Society Of Cardiology , Clinical Research , Research Council , Cardiovascular Research Foundation , American College Of Cardiology , British Cardiovascular Intervention Society , Drug Administration , Md Indiana University School Of Medicine , Md Penn State Health , Envision Change , Transforming Clinical ,

GPs likely to see surge in serious heart problems because of COVID lockdown

The COVID-19 lockdown in the first half of 2020 may lead to a surge in heart failure and mechanical heart problems formerly consigned to textbooks, according to a cardiology expert. ....

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