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UCF Scientist Discovers Roots of Antibiotic Resistance

UCF Scientist Discovers Roots of Antibiotic Resistance
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United States , El Salvador , College Of Medicine , Suhtling Wong , Salvador Almagro Moreno ,

UCF scientist uncovers roots of antibiotic re

In a recent article published in PLoS Genetics, UCF College of Medicine microbiologist Salvador Almagro-Moreno uncovers the evolutionary origins of antimicrobial resistance (AMR) in bacteria. His studies on the bacterium that causes cholera, Vibrio cholerae, provide insight into deciphering what conditions must occur for infectious agents to become resistant. He studied genetic variants of a protein found in bacterial membranes called OmpU. Using computational and molecular approaches, his team found that several OmpU mutations in the cholera bacteria led to resistance to numerous antimicrobial agents. This resistance included antimicrobial peptides that act as defenses in the human gut. ....

El Salvador , United States , College Of Medicine , Method Of Research , Suhtling Wong ,