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C4 Therapeutics : CTOS 2023 - CFT8634 Phase 1 Dose Escalation -November 01, 2023 at 07:19 am EDT

Initial Results From A Phase 1 Study of CFT8634, A Novel Bifunctional Degradation Activating Compound of BRD9, in Synovial Sarcoma and SMARCB1-Null Tumors

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Ammax Bio , Daiihi Sankyo , Daiichi Sankyo , Eli Lilly , Jazz Pharmaceuticals , Sarcoma Alliance For Research , Ayala Pharmaceuticals , Therapeutics Inc , Certis Oncology Solutions , Salarius Pharmaceuticals , Threshold Pharmaceuticals , Health Advances , Kowa Research Institute , Humans In Health , Research To Practice , Desmoid Tumor Research Foundation , Theseus Pharmaceuticals , Boehringer Ingelheim , Novo Holdings , Eastern Cooperative Oncology Group , Servier Pharmaceuticals , Common Terminology Criteria , Adverse Events , Positron Emission Tomography , Computed Tomography , Response Evaluation Criteria ,

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets. ....

Kateryna Kon Shutterstock , Cancer Research Industry , Cancer Research , Nature Genetics , Sucrose Non Fermentable , Matrix Associated , Actin Dependent Regulator Of Chromatin , Research Industry Focus , Image Credit , Regularly Interspaced Short Palindromic Repeats , Ars Cov 2 , Adenosine Triphosphate , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

The Power of 3D Spatial Genomics

Dovetail Genomics describes how drug development can benefit from technology that reveals chromatin’s topological changes. ....

Michigan Center , United States , Arul Chinnaiyan , Abhijit Parolia , Todd Dickinson , University Of Michigan , Sucrose Non Fermentable , Dovetail Genomics , Translational Pathology ,