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Mitsubishi Tanabe Pharma America Announces FDA Approval of RADICAVA ORS® (edaravone) for the Treatment of ALS

/PRNewswire/ Mitsubishi Tanabe Pharma America, Inc. (MTPA) today announced the U.S. Food and Drug Administration (FDA) has approved RADICAVA ORS®. ....

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Mitsubishi Tanabe Pharma America Announces FDA Approval of RADICAVA ORS® (edaravone) for the Treatment of ALS

Mitsubishi Tanabe Pharma America Announces FDA Approval of RADICAVA ORS® (edaravone) for the Treatment of ALS
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More Than 400 Studies on the Failure of Compulsory Covid Interventions

The great body of evidence shows that COVID-19 lockdowns, shelter-in-place policies, masks, school closures, and mask mandates have . ....

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More Than 150 Comparative Studies and Articles on Mask Ineffectiveness and Harms

Commentary It is not unreasonable to conclude that surgical and cloth masks, used as they currently are being . ....

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How to Optimize Success in Clinical Trials of Antidepressants

How to Optimize Success in Clinical Trials of Antidepressants
By Paula Jacobsen, Ph.D., and Nick DeMartinis, M.D., Praxis Precision Medicines
This is an exceptionally exciting time to be developing therapies for patients suffering from depressive disorders. Advances in antidepressant pharmacology have led to diverse and promising therapeutic options. However, it is important to acknowledge the challenges of conducting clinical trials for major depressive disorder (MDD).
Chief among these challenges is the sensitivity of clinical trial methodology for demonstration of efficacy in MDD. A meta-analysis of antidepressant programs that included FDA-approved antidepressant clinical trial data from randomized, double-blind, placebo-controlled acute treatment studies conducted between 1995 and 2008 revealed that only 50% were successful despite the inclusion of only studies that evaluated doses in the approved therapeutic range. ....

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